Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813696 | 0.93 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1TDP1S1PR1SGPL1 | |
| SCHEMBL9813777 | 0.89 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1TDP1TSHRGAA | |
| SCHEMBL11860026 | 0.77 | MEN1 (0.39) | ALDH1A1TDP1EPHX2 | |
| SCHEMBL14658202 | 0.75 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL125382 | 0.75 | — | — | |
| SCHEMBL4727634 | 0.74 | CYP1A2 (0.43) | ALDH1A1TDP1TSHRGAARECQL | |
| SCHEMBL12214257 | 0.73 | GAA (0.33) | SMN1; SMN2CYP3A4GAARECQLEPHX2 | |
| SCHEMBL15928441 | 0.73 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1TDP1TSHR | |
| Ether SCHEMBL8479704 | 0.71 | CYP2D6 (0.33) | SMN1; SMN2GAAEPHX2 | |
| SCHEMBL13107064 | 0.71 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1TDP1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0163245-B1 | DERIVATIVES OF ALKYL-SUBSTITUTED 4-HYDROXY-METHYL-PIPERIDINE AND USE THEREOF AS STABILIZERS | AUSIMONT S.r.l. (IT) | 1991-07-31 | — | — | EP | disclosed |
| US-4772708-A | STABILIZERS FOR POLYMERS | AUSIMONT S.P.A. (IT) | 1988-09-20 | — | — | US | disclosed |
| EP-0163245-A2 | Derivatives of alkyl-substituted 4-hydroxy-methyl-piperidine and use thereof as stabilizers | AUSIMONT S.r.l. (IT) | 1985-12-04 | — | — | EP | disclosed |