Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.34 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | PRKCG | P05129 | 1/20 | 0.32 |
| ▸ | PRKCB | P05771 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | PRKCH | P24723 | 1/20 | 0.32 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813587 | 0.93 | SMN1; SMN2 (0.44) | ALDH1A1TDP1SMN1; SMN2EPHX2SGPL1 | |
| SCHEMBL9813777 | 0.93 | ALDH1A1 (0.36) | ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL11860026 | 0.85 | MEN1 (0.39) | ALDH1A1TDP1HTTMEN1THRB | |
| SCHEMBL8434237 | 0.77 | ALDH1A1 (0.61) | ALDH1A1TDP1SMN1; SMN2HTTMEN1 | |
| SCHEMBL130841 | 0.77 | ALDH1A1 (0.61) | ALDH1A1TDP1SMN1; SMN2HTTMEN1 | |
| SCHEMBL13923572 | 0.77 | ALDH1A1 (0.61) | ALDH1A1TDP1SMN1; SMN2HTTMEN1 | |
| SCHEMBL16912862 | 0.76 | ALDH1A1 (0.39) | ALDH1A1THRBS1PR1 | |
| SCHEMBL9516918 | 0.76 | ALDH1A1 (0.39) | ALDH1A1THRBS1PR1 | |
| SCHEMBL15570217 | 0.76 | ALDH1A1 (0.39) | ALDH1A1THRBS1PR1 | |
| SCHEMBL15707671 | 0.76 | ALDH1A1 (0.39) | ALDH1A1THRBS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0163245-B1 | DERIVATIVES OF ALKYL-SUBSTITUTED 4-HYDROXY-METHYL-PIPERIDINE AND USE THEREOF AS STABILIZERS | AUSIMONT S.r.l. (IT) | 1991-07-31 | — | — | EP | disclosed |
| US-4772708-A | STABILIZERS FOR POLYMERS | AUSIMONT S.P.A. (IT) | 1988-09-20 | — | — | US | disclosed |
| EP-0163245-A2 | Derivatives of alkyl-substituted 4-hydroxy-methyl-piperidine and use thereof as stabilizers | AUSIMONT S.r.l. (IT) | 1985-12-04 | — | — | EP | disclosed |