Methyl Carbamate

Methyl Carbamate

SCHEMBL9813642

CC1CC(C)(C)N(Cc2ccccc2)C(C)(C)C1.COC(N)=O

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
AMPD2 Q01433 5/20 0.43
NR1H2 P55055 1/20 0.42
ALDH1A1 P00352 5/20 0.41
MAPT P10636 3/20 0.41
TSHR P16473 3/20 0.40
ALOX15 P16050 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HSD17B10 Q99714 1/20 0.40
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
CYP3A4 P08684 2/20 0.40
KDM4E B2RXH2 1/20 0.40
LMNA P02545 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CYP2D6 P10635 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL9813576 0.87 AMPD2 (0.47) AMPD2ALDH1A1MAPTTSHRSMN1; SMN2
Benzoic Acid SCHEMBL9813580 0.83 OPRD1 (0.41) AMPD2ALDH1A1MAPTTSHRSMN1; SMN2
Sebacic Acid SCHEMBL9813717 0.81 MAPT (0.46) AMPD2ALDH1A1MAPTTSHRSMN1; SMN2
Sebacic Acid SCHEMBL10676479 0.81 MAPT (0.46) AMPD2ALDH1A1MAPTTSHRSMN1; SMN2
Crotonic Acid SCHEMBL9813584 0.80 MEN1 (0.41) AMPD2ALDH1A1MAPTTSHRSMN1; SMN2
Crotonic Acid SCHEMBL10953476 0.80 MEN1 (0.41) AMPD2ALDH1A1MAPTTSHRSMN1; SMN2
Stearic Acid SCHEMBL9813592 0.77 ALDH1A1 (0.43) ALDH1A1MAPTTSHRALOX15HSD17B10
SCHEMBL11403013 0.77 TSHR (0.44) AMPD2NR1H2ALDH1A1MAPTTSHR
SCHEMBL28507735 0.76 GAA (0.44) AMPD2ALDH1A1SMN1; SMN2KMT2AKDM4E
SCHEMBL39509 0.75 KMT2A (0.44) AMPD2ALDH1A1MAPTTSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0163245-B1 DERIVATIVES OF ALKYL-SUBSTITUTED 4-HYDROXY-METHYL-PIPERIDINE AND USE THEREOF AS STABILIZERS AUSIMONT S.r.l. (IT) 1991-07-31 EP disclosed
US-4772708-A STABILIZERS FOR POLYMERS AUSIMONT S.P.A. (IT) 1988-09-20 US disclosed
EP-0163245-A2 Derivatives of alkyl-substituted 4-hydroxy-methyl-piperidine and use thereof as stabilizers AUSIMONT S.r.l. (IT) 1985-12-04 EP disclosed