Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | EZH2 | Q15910 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10679466 | 1.00 | KMT2A (0.44) | KMT2APOLBGAAEZH2HTT | |
| SCHEMBL9813680 | 0.92 | KMT2A (0.52) | KMT2AGAAKDM4EMEN1MAPT | |
| SCHEMBL10680690 | 0.77 | HSD17B10 (0.42) | KMT2APOLBHTTKDM4EMEN1 | |
| SCHEMBL9813714 | 0.77 | HSD17B10 (0.42) | KMT2APOLBHTTKDM4EMEN1 | |
| SCHEMBL14549202 | 0.76 | KDM4E (0.52) | KMT2APOLBGAAKDM4EMEN1 | |
| SCHEMBL9813708 | 0.74 | P2RX7 (0.43) | KMT2APOLBGAAHTTMEN1 | |
| Hydrochloric Acid SCHEMBL11403968 | 0.74 | KDM4E (0.50) | KMT2APOLBGAAKDM4EMEN1 | |
| Naphthoic Acid SCHEMBL9813601 | 0.73 | KMT2A (0.62) | KMT2APOLBGAAEZH2HTT | |
| SCHEMBL10679780 | 0.73 | EZH2 (0.51) | KMT2APOLBEZH2MEN1L3MBTL1 | |
| SCHEMBL10682367 | 0.73 | KMT2A (0.44) | KMT2APOLBGAAEZH2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0163245-B1 | DERIVATIVES OF ALKYL-SUBSTITUTED 4-HYDROXY-METHYL-PIPERIDINE AND USE THEREOF AS STABILIZERS | AUSIMONT S.r.l. (IT) | 1991-07-31 | — | — | EP | disclosed |
| EP-0163245-A2 | Derivatives of alkyl-substituted 4-hydroxy-methyl-piperidine and use thereof as stabilizers | AUSIMONT S.r.l. (IT) | 1985-12-04 | — | — | EP | disclosed |