Naphthoic Acid

Naphthoic Acid

SCHEMBL9813601

CC1CC(C)(C)NC(C)(C)C1.O=C(O)c1cccc2ccccc12

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.62
NR4A1 P22736 1/20 0.58
NR4A2 P43354 1/20 0.58
NR4A3 Q92570 1/20 0.58
ALOX15 P16050 1/20 0.49
CDC25B P30305 1/20 0.49
GAA P10253 1/20 0.43
KDM4E B2RXH2 1/20 0.42
PLK1 P53350 1/20 0.42
PTPN1 P18031 2/20 0.41
WDR5 P61964 1/20 0.41
POLB P06746 1/20 0.40
LDHA P00338 1/20 0.40
MMP3 P08254 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
GFER P55789 1/20 0.39
CXCR5 P32302 1/20 0.39
EZH2 Q15910 1/20 0.39
MCL1 Q07820 1/20 0.39
ACMSD Q8TDX5 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Salicylic Acid SCHEMBL9813624 0.81 ALDH1A1 (0.55) KMT2AALOX15GAAKDM4EPOLB
SCHEMBL9813680 0.80 KMT2A (0.52) KMT2AGAAKDM4EMEN1MAPT
Naphthoic Acid SCHEMBL30507709 0.78 NR4A1 (0.95) KMT2ANR4A1NR4A2NR4A3ALOX15
SCHEMBL9813709 0.78 ALOX15 (0.46) KMT2AALOX15GAAKDM4EPOLB
Phthalic Acid SCHEMBL11485468 0.77 ALOX15 (0.61) KMT2AALOX15GAAKDM4EPOLB
Benzoic Acid SCHEMBL9813692 0.77 GAA (0.58) KMT2AALOX15GAAKDM4EPOLB
Pyromellitic Acid SCHEMBL10684063 0.77 ALOX15 (0.46) KMT2AALOX15GAAKDM4EPOLB
Pyromellitic Acid SCHEMBL9813658 0.77 ALOX15 (0.46) KMT2AALOX15GAAKDM4EPOLB
Naphthoic Acid SCHEMBL30401620 0.77 NR4A1 (0.91) KMT2ANR4A1NR4A2NR4A3ALOX15
Naphthoic Acid SCHEMBL17258 0.76 NR4A1 (1.00) KMT2ANR4A1NR4A2NR4A3ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0163245-B1 DERIVATIVES OF ALKYL-SUBSTITUTED 4-HYDROXY-METHYL-PIPERIDINE AND USE THEREOF AS STABILIZERS AUSIMONT S.r.l. (IT) 1991-07-31 EP disclosed
US-4772708-A STABILIZERS FOR POLYMERS AUSIMONT S.P.A. (IT) 1988-09-20 US disclosed
EP-0163245-A2 Derivatives of alkyl-substituted 4-hydroxy-methyl-piperidine and use thereof as stabilizers AUSIMONT S.r.l. (IT) 1985-12-04 EP disclosed