Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10679780 | 0.84 | EZH2 (0.51) | ALDH1A1MEN1KMT2AEPHX2NPSR1 | |
| SCHEMBL10682367 | 0.84 | KMT2A (0.44) | ALDH1A1MEN1KMT2ANPSR1TSHR | |
| 4-Chloro-Benzoic Acid SCHEMBL9813857 | 0.81 | ALOX15 (0.53) | ALDH1A1MEN1KMT2ACCR2TSHR | |
| SCHEMBL9813714 | 0.80 | HSD17B10 (0.42) | ALDH1A1MEN1KMT2ANPSR1POLB | |
| SCHEMBL10680690 | 0.80 | HSD17B10 (0.42) | ALDH1A1MEN1KMT2ANPSR1POLB | |
| SCHEMBL1287379 | 0.76 | MEN1 (0.52) | ALDH1A1MEN1KMT2ANPSR1POLB | |
| SCHEMBL11057664 | 0.76 | GAA (0.49) | P2RX7ALDH1A1MEN1KMT2AEPHX2 | |
| SCHEMBL1507740 | 0.76 | NPC1 (0.64) | ALDH1A1MEN1KMT2AEPHX2TSHR | |
| SCHEMBL9230108 | 0.74 | RAB9A (0.56) | ALDH1A1MEN1KMT2ANPSR1TSHR | |
| SCHEMBL10679466 | 0.74 | KMT2A (0.44) | ALDH1A1MEN1KMT2ATSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0163245-B1 | DERIVATIVES OF ALKYL-SUBSTITUTED 4-HYDROXY-METHYL-PIPERIDINE AND USE THEREOF AS STABILIZERS | AUSIMONT S.r.l. (IT) | 1991-07-31 | — | — | EP | disclosed |
| US-4772708-A | STABILIZERS FOR POLYMERS | AUSIMONT S.P.A. (IT) | 1988-09-20 | — | — | US | disclosed |
| EP-0163245-A2 | Derivatives of alkyl-substituted 4-hydroxy-methyl-piperidine and use thereof as stabilizers | AUSIMONT S.r.l. (IT) | 1985-12-04 | — | — | EP | disclosed |