4-Chloro-Benzoic Acid

4-Chloro-Benzoic Acid

SCHEMBL9813857

CC1CC(C)(C)NC(C)(C)C1.O=C(O)c1ccc(Cl)cc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.53
TSHR P16473 1/20 0.53
SRD5A2 P31213 1/20 0.49
CCR2 P41597 1/20 0.47
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
GAA P10253 1/20 0.43
EZH2 Q15910 3/20 0.43
ALDH1A1 P00352 1/20 0.41
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
USP2 O75604 1/20 0.40
RARA P10276 1/20 0.39
RARB P10826 1/20 0.39
RARG P13631 1/20 0.39
GLA P06280 1/20 0.39
NR4A2 P43354 1/20 0.39
KDM4E B2RXH2 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid SCHEMBL9813692 0.85 GAA (0.58) ALOX15TSHRSRD5A2CCR2MEN1
SCHEMBL9813651 0.82 SRD5A2 (0.54) SRD5A2KMT2AGAAEZH2RXRA
P-Anisic Acid SCHEMBL9813609 0.82 CA1 (0.59) GAAEZH2ALDH1A1RXRAKDM4E
SCHEMBL10679973 0.82 GAA (0.45) ALOX15MEN1KMT2AGAAEZH2
SCHEMBL9813708 0.81 P2RX7 (0.43) TSHRCCR2MEN1KMT2AGAA
SCHEMBL9813697 0.79 ALOX15 (0.45) ALOX15MEN1KMT2AGAAEZH2
SCHEMBL10681714 0.79 ALOX15 (0.45) ALOX15MEN1KMT2AGAAEZH2
Pyromellitic Acid SCHEMBL10684063 0.75 ALOX15 (0.46) ALOX15CCR2MEN1KMT2AGAA
Pyromellitic Acid SCHEMBL9813658 0.75 ALOX15 (0.46) ALOX15CCR2MEN1KMT2AGAA
SCHEMBL17067286 0.74 MEN1 (0.71) MEN1KMT2AEZH2GLASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0163245-B1 DERIVATIVES OF ALKYL-SUBSTITUTED 4-HYDROXY-METHYL-PIPERIDINE AND USE THEREOF AS STABILIZERS AUSIMONT S.r.l. (IT) 1991-07-31 EP disclosed
US-4772708-A STABILIZERS FOR POLYMERS AUSIMONT S.P.A. (IT) 1988-09-20 US disclosed
EP-0163245-A2 Derivatives of alkyl-substituted 4-hydroxy-methyl-piperidine and use thereof as stabilizers AUSIMONT S.r.l. (IT) 1985-12-04 EP disclosed