Methyl Carbamate

Methyl Carbamate

SCHEMBL9813718

CCCCN1C(C)(C)CC(C)CC1(C)C.COC(N)=O

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 6/20 0.35
UBE2M P61081 1/20 0.34
DCUN1D1 Q96GG9 1/20 0.34
EPHX1 P07099 2/20 0.33
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
POLA1 P09884 1/20 0.31
OGA O60502 1/20 0.31
TRPV1 Q8NER1 4/20 0.30
CNR1 P21554 2/20 0.30
CNR2 P34972 2/20 0.30
MAPK1 P28482 1/20 0.30
HPGD P15428 1/20 0.30
HTR4 Q13639 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Carbamate SCHEMBL9813625 0.85 PAOX (0.30)
SCHEMBL1702770 0.80 ATM (0.37) UBE2MDCUN1D1ALDH1A1GAAHSD17B10
Hexanoate SCHEMBL9813711 0.79 AKR1B1 (0.48) ALDH1A1HSD17B10CYP2C9CYP2C19
SCHEMBL14001177 0.77 EBP (0.40) EPHX2
SCHEMBL11395651 0.74 NAAA (0.37) EPHX2UBE2MDCUN1D1EPHX1GAA
Cyclohexane SCHEMBL9813712 0.74 CHRM2 (0.33) CYP2C19
SCHEMBL11444804 0.72 APLNR (0.45) UBE2MDCUN1D1ALDH1A1CYP2C19
SCHEMBL15489686 0.72
SCHEMBL21985843 0.72
SCHEMBL27844515 0.72 CYP3A4 (0.38) EPHX2EPHX1CYP3A4CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0163245-B1 DERIVATIVES OF ALKYL-SUBSTITUTED 4-HYDROXY-METHYL-PIPERIDINE AND USE THEREOF AS STABILIZERS AUSIMONT S.r.l. (IT) 1991-07-31 EP disclosed
US-4772708-A STABILIZERS FOR POLYMERS AUSIMONT S.P.A. (IT) 1988-09-20 US disclosed
EP-0163245-A2 Derivatives of alkyl-substituted 4-hydroxy-methyl-piperidine and use thereof as stabilizers AUSIMONT S.r.l. (IT) 1985-12-04 EP disclosed