Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GRK2 | P25098 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813860 | 0.88 | CYP2C9 (0.44) | PPARGPPARAKMT2APOLBGRK2 | |
| SCHEMBL9813854 | 0.84 | KMT2A (0.44) | PPARGPPARAKMT2APOLBGRK2 | |
| SCHEMBL9813834 | 0.81 | KMT2A (0.43) | PPARGPPARAKMT2APOLBGRK2 | |
| SCHEMBL10452836 | 0.81 | TBXA2R (0.62) | PPARGKMT2AALDH1A1GAAMEN1 | |
| SCHEMBL9813451 | 0.80 | CA2 (0.51) | KMT2APOLBGRK2HDAC1HDAC8 | |
| SCHEMBL10452733 | 0.77 | TBXA2R (0.60) | PPARGKMT2AALDH1A1GAAMEN1 | |
| SCHEMBL9813760 | 0.77 | KMT2A (0.47) | KMT2APOLBGRK2HDAC1HDAC8 | |
| SCHEMBL10580731 | 0.76 | HDAC1 (0.56) | KMT2APOLBGRK2HDAC1HDAC8 | |
| SCHEMBL3250400 | 0.76 | TBXA2R (0.62) | KMT2APOLBGRK2HDAC1HDAC8 | |
| SCHEMBL3392694 | 0.74 | PPARG (0.59) | PPARGPPARAPOLBCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301421-B1 | SULFUR COMPOUNDS, PROCESS FOR THEIR PREPARATION AND MEDICINES | Roche Diagnostics GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |