Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GRK2 | P25098 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813854 | 0.96 | KMT2A (0.44) | KMT2APOLBGRK2CYP2C9CYP2C19 | |
| SCHEMBL10453021 | 0.83 | ALDH1A1 (0.59) | KMT2AALDH1A1GAAMEN1TBXA2R | |
| SCHEMBL9813722 | 0.81 | PPARG (0.42) | KMT2APOLBGRK2CYP2C9CYP2C19 | |
| SCHEMBL10452830 | 0.81 | TBXA2R (0.61) | KMT2AALDH1A1PPARGGAAMEN1 | |
| SCHEMBL15546561 | 0.79 | KMT2A (0.54) | KMT2APOLBCYP2C9CYP2C19MEN1 | |
| SCHEMBL9813860 | 0.79 | CYP2C9 (0.44) | KMT2APOLBGRK2CYP2C9CYP2C19 | |
| SCHEMBL10452825 | 0.79 | TBXAS1 (0.46) | KMT2APOLBCYP2C9CYP2C19GAA | |
| SCHEMBL10451967 | 0.78 | TBXA2R (0.44) | KMT2APOLBGRK2CYP2C9CYP2C19 | |
| SCHEMBL10453024 | 0.78 | TBXA2R (0.58) | KMT2AALDH1A1PPARGGAAMEN1 | |
| SCHEMBL10584188 | 0.76 | TBXA2R (0.60) | KMT2APOLBGRK2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301421-B1 | SULFUR COMPOUNDS, PROCESS FOR THEIR PREPARATION AND MEDICINES | Roche Diagnostics GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |
| EP-0301421-A2 | Sulfur compounds, process for their preparation and medicines | Roche Diagnostics GmbH (DE) | 1989-02-01 | — | — | EP | disclosed |