Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | SGMS1 | Q86VZ5 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768486 | 0.96 | PTGIR (0.55) | PTGIRALDH1A1TBXA2RTBXAS1SGMS1 | |
| SCHEMBL9813750 | 0.85 | PPARA (0.59) | PTGIRCA12CA1CA2CA4 | |
| SCHEMBL9813734 | 0.84 | TBXA2R (0.64) | PTGIRALDH1A1TBXA2RTBXAS1PSEN1 | |
| SCHEMBL9813798 | 0.83 | PTGIR (0.55) | PTGIRALDH1A1TBXA2RTBXAS1SGMS1 | |
| SCHEMBL10584188 | 0.82 | TBXA2R (0.60) | ALDH1A1TBXA2RCA12CA1CA2 | |
| SCHEMBL9813754 | 0.82 | TBXA2R (0.55) | ALDH1A1TBXA2RTBXAS1PSEN1PSEN2 | |
| SCHEMBL9813812 | 0.81 | PPARA (0.57) | PTGIRCA12CA1CA2CA4 | |
| SCHEMBL9813773 | 0.80 | TBXA2R (0.65) | PTGIRALDH1A1TBXA2RTBXAS1 | |
| SCHEMBL9768506 | 0.79 | SGMS1 (0.58) | ALDH1A1TBXA2RTBXAS1SGMS1ADAMTS5 | |
| SCHEMBL9813830 | 0.79 | PTGDR2 (0.47) | GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301421-B1 | SULFUR COMPOUNDS, PROCESS FOR THEIR PREPARATION AND MEDICINES | Roche Diagnostics GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |
| EP-0301421-A2 | Sulfur compounds, process for their preparation and medicines | Roche Diagnostics GmbH (DE) | 1989-02-01 | — | — | EP | disclosed |