Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 2/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.45 |
| ▸ | SGMS1 | Q86VZ5 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768486 | 0.87 | PTGIR (0.55) | PTGIRTBXA2RTBXAS1ALDH1A1PPARG | |
| SCHEMBL7629584 | 0.85 | PTGIR (0.47) | PTGIRTBXA2RTBXAS1ALDH1A1PPARG | |
| SCHEMBL9813770 | 0.83 | PTGIR (0.54) | PTGIRTBXA2RTBXAS1ALDH1A1ADAMTS5 | |
| SCHEMBL9813749 | 0.82 | PPARA (0.55) | TBXA2RTBXAS1PPARGPPARA | |
| SCHEMBL11339358 | 0.80 | TBXA2R (0.60) | PTGIRTBXA2RTBXAS1ALDH1A1ADAMTS5 | |
| SCHEMBL9813836 | 0.79 | ALDH1A1 (0.53) | PTGIRTBXA2RTBXAS1ALDH1A1PPARA | |
| SCHEMBL30969690 | 0.78 | ALOX15 (0.65) | PTGIRALDH1A1MCL1MAP4K4FFAR1 | |
| SCHEMBL40485 | 0.78 | ALOX15 (0.65) | PTGIRALDH1A1MCL1MAP4K4FFAR1 | |
| SCHEMBL9813734 | 0.77 | TBXA2R (0.64) | PTGIRTBXA2RTBXAS1ALDH1A1PPARA | |
| SCHEMBL11377919 | 0.77 | LMNA (0.56) | PTGIRTBXAS1ALDH1A1PPARGNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301421-B1 | SULFUR COMPOUNDS, PROCESS FOR THEIR PREPARATION AND MEDICINES | Roche Diagnostics GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |
| EP-0301421-A2 | Sulfur compounds, process for their preparation and medicines | Roche Diagnostics GmbH (DE) | 1989-02-01 | — | — | EP | disclosed |