Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS1 | Q86VZ5 | 4/20 | 0.58 |
| ▸ | EGFR | P00533 | 3/20 | 0.55 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.50 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768486 | 0.83 | PTGIR (0.55) | SGMS1ADAMTS5ADAMTS4TBXA2RTBXAS1 | |
| SCHEMBL9813770 | 0.79 | PTGIR (0.54) | SGMS1ADAMTS5ADAMTS4TBXA2RTBXAS1 | |
| SCHEMBL9813734 | 0.79 | TBXA2R (0.64) | TBXA2RTBXAS1PPARAALDH1A1 | |
| SCHEMBL451086 | 0.76 | S1PR1 (0.62) | SGMS1EGFRERBB2ADAMTS5ADAMTS4 | |
| SCHEMBL9813754 | 0.75 | TBXA2R (0.55) | TBXA2RTBXAS1PPARAALDH1A1 | |
| SCHEMBL9320853 | 0.74 | GAA (0.62) | GAAHTTALDH1A1 | |
| Acetic Acid SCHEMBL362668 | 0.74 | ALDH1A1 (0.55) | GAAHTTALDH1A1 | |
| SCHEMBL9813773 | 0.72 | TBXA2R (0.65) | TBXA2RTBXAS1PPARAALDH1A1 | |
| SCHEMBL9813812 | 0.72 | PPARA (0.57) | PPARA | |
| SCHEMBL9768505 | 0.72 | ADAM17 (0.47) | GAAPPARAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5070099-A | THROMBOXANE ANTAGONISTS | E. R. SQUIBB & SONS, INC. (US) | 1991-12-03 | — | — | US | disclosed |
| US-5006542-A | Cardiovascular agents | E. R. SQUIBB & SONS, INC. (US) | 1991-04-09 | — | — | US | disclosed |