Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 1/20 | 0.55 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.51 |
| ▸ | MMP12 | P39900 | 2/20 | 0.51 |
| ▸ | MMP13 | P45452 | 2/20 | 0.51 |
| ▸ | PPARD | Q03181 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | MMP14 | P50281 | 2/20 | 0.49 |
| ▸ | MMP7 | P09237 | 1/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.48 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.48 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.48 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.48 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.48 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813734 | 0.92 | TBXA2R (0.64) | TBXA2RTBXAS1ALDH1A1FFAR1PPARD | |
| SCHEMBL9768486 | 0.86 | PTGIR (0.55) | TBXA2RTBXAS1ALDH1A1PPARGPSEN1 | |
| SCHEMBL9813773 | 0.85 | TBXA2R (0.65) | TBXA2RTBXAS1ALDH1A1FFAR1MMP12 | |
| SCHEMBL9813770 | 0.82 | PTGIR (0.54) | TBXA2RTBXAS1ALDH1A1PSEN1PSEN2 | |
| SCHEMBL422442 | 0.78 | ALOX15 (0.76) | ALDH1A1FFAR1PPARDPPARGALOX15 | |
| SCHEMBL9813836 | 0.78 | ALDH1A1 (0.53) | TBXA2RTBXAS1ALDH1A1FFAR1PPARD | |
| SCHEMBL9813851 | 0.78 | PPARA (0.62) | TBXA2RTBXAS1FFAR1PPARGHDAC1 | |
| SCHEMBL4530835 | 0.76 | PPARD (0.77) | FFAR1MMP12PPARDPPARGMMP2 | |
| SCHEMBL28669666 | 0.75 | ALOX15 (0.70) | TBXA2RTBXAS1ALDH1A1FFAR1PPARD | |
| SCHEMBL9768506 | 0.75 | SGMS1 (0.58) | TBXA2RTBXAS1ALDH1A1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301421-B1 | SULFUR COMPOUNDS, PROCESS FOR THEIR PREPARATION AND MEDICINES | Roche Diagnostics GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |
| EP-0301421-A2 | Sulfur compounds, process for their preparation and medicines | Roche Diagnostics GmbH (DE) | 1989-02-01 | — | — | EP | disclosed |