Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | CYP51A1 | Q16850 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9782289 | 0.87 | CYP51A1 (0.57) | ADRB3CYP51A1 | |
| SCHEMBL9813959 | 0.87 | MEN1 (0.43) | MEN1KMT2AADRB3KDM4ECYP51A1 | |
| SCHEMBL9813873 | 0.87 | ADRB3 (0.48) | MEN1KMT2AADRB3CYP51A1CYP1A2 | |
| SCHEMBL9813877 | 0.87 | ADRB3 (0.48) | MEN1KMT2AADRB3CYP51A1CYP1A2 | |
| SCHEMBL9813880 | 0.87 | ADRB3 (0.48) | MEN1KMT2AADRB3CYP51A1CYP1A2 | |
| SCHEMBL9782091 | 0.84 | THRA (0.40) | MEN1KMT2AADRB3KDM4EBCHE | |
| SCHEMBL9782109 | 0.80 | THRA (0.38) | MEN1KMT2AADRB3KDM4EBCHE | |
| SCHEMBL9813947 | 0.80 | MEN1 (0.45) | MEN1KMT2AADRB3ALDH1A1TAAR1 | |
| SCHEMBL9813906 | 0.79 | ADRB3 (0.45) | MEN1KMT2AADRB3CYP1A2CYP2D6 | |
| SCHEMBL9782603 | 0.79 | CYP51A1 (0.37) | MEN1KMT2AADRB3CYP51A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017619-A | Anitdiabetic | HOFFMANN-LA ROCHE INC. (US) | 1991-05-21 | — | — | US | disclosed |