Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10519397 | 0.87 | TLR2 (0.45) | ALDH1A1 | |
| SCHEMBL31751541 | 0.87 | ALDH1A1 (0.51) | HTTFOLH1SMN1; SMN2LPAR1ALDH1A1 | |
| SCHEMBL13058704 | 0.80 | TBXAS1 (0.50) | TBXAS1ALDH1A1 | |
| SCHEMBL3757478 | 0.80 | TBXAS1 (0.50) | TBXAS1ALDH1A1 | |
| SCHEMBL6139421 | 0.80 | SLC1A1 (0.48) | FOLH1MAPK1SLC1A1CA1CA2 | |
| SCHEMBL828710 | 0.79 | ALDH1A1 (0.57) | FOLH1MAPK1SLC6A3SLC1A1CA1 | |
| SCHEMBL828709 | 0.79 | ALDH1A1 (0.57) | FOLH1MAPK1SLC6A3SLC1A1CA1 | |
| SCHEMBL828711 | 0.79 | ALDH1A1 (0.57) | FOLH1MAPK1SLC6A3SLC1A1CA1 | |
| SCHEMBL2587051 | 0.78 | ALDH1A1 (0.61) | HTTMAPK1HDAC3ADRA1AHDAC4 | |
| SCHEMBL6367935 | 0.78 | ALDH1A1 (0.65) | SMN1; SMN2LPAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988497-A | Diagnostic test for acute pancreatitus or cancer of the pancreas; sensitivity; colorimetry S | BOEHRINGER MANNHEIM GMBH (DE) | 1991-01-29 | — | — | US | disclosed |
| US-4847376-A | COLORIMETRIC ANALYSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-07-11 | — | — | US | disclosed |