SCHEMBL9814181

SCHEMBL9814181

CC(=O)N(C(C)=O)c1cc(O)ccc1Cl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.45
GAA P10253 2/20 0.42
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA7 P43166 2/20 0.41
CA9 Q16790 2/20 0.41
CA14 Q9ULX7 2/20 0.41
FSCN1 Q16658 1/20 0.41
MEN1 O00255 2/20 0.40
CYP1A2 P05177 2/20 0.40
KMT2A Q03164 2/20 0.40
CYP3A4 P08684 1/20 0.40
ALDH1A1 P00352 2/20 0.38
LMNA P02545 2/20 0.38
HPGD P15428 2/20 0.38
CASP1 P29466 2/20 0.38
BRCA1 P38398 2/20 0.38
RGS12 O14924 1/20 0.38
USP2 O75604 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25969090 0.80 ALDH1A1 (0.53) HSD17B10GAACA12CA1CA2
SCHEMBL4804520 0.79 GAA (0.41) GAAFSCN1ALDH1A1APEX1
SCHEMBL11506289 0.79 FSCN1 (0.48) HSD17B10GAAFSCN1KMT2AALDH1A1
SCHEMBL25969084 0.78 GAA (0.47) HSD17B10GAACA12CA1CA2
SCHEMBL9493720 0.75 HSD17B10 (0.52) HSD17B10GAACA12CA1CA2
Acetone SCHEMBL27351306 0.71 HSD17B10 (0.52) HSD17B10CA12CA1CA2CA7
SCHEMBL31305311 0.71 FSCN1 (0.70) HSD17B10GAAFSCN1MEN1KMT2A
SCHEMBL7306944 0.69 HSD17B10 (0.50) HSD17B10GAACA12CA1CA2
SCHEMBL25969102 0.68 GAA (0.59) GAACYP1A2ALDH1A1HPGDMAPT
SCHEMBL25969106 0.68 MCL1 (0.65) GAAMEN1KMT2AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0244697-B1 SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1991-08-28 EP disclosed
US-4746602-A FREE FROM WHITE BACKGROUND STAINS FUJI PHOTO FILM CO., LTD. (JP) 1988-05-24 US disclosed
EP-0244697-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1987-11-11 EP disclosed