Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9814623 | 0.84 | NFKB1 (0.30) | NFKB1TRPA1 | |
| SCHEMBL11760973 | 0.82 | — | — | |
| SCHEMBL11760961 | 0.82 | — | — | |
| SCHEMBL4538880 | 0.78 | — | — | |
| SCHEMBL10398161 | 0.78 | CCR2 (0.38) | LMNAALDH1A1 | |
| SCHEMBL28690185 | 0.78 | CCR2 (0.33) | ALDH1A1 | |
| SCHEMBL5693430 | 0.77 | — | — | |
| Ethylamine SCHEMBL7593052 | 0.77 | — | — | |
| SCHEMBL973819 | 0.75 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL973821 | 0.75 | ALDH1A1 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260838-B1 | TITANIUM, ZIRCONIUM AND HAFNIUM ENOLATES AS INITIATORS IN THE POLYMERIZATION OF ACRYLIC MONOMERS TO \"LIVING\" POLYMERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-09-04 | — | — | EP | disclosed |
| US-4783500-A | ORGANO-SILICON,-TIN, OR -GERMANIUM INITIATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-11-08 | — | — | US | disclosed |
| EP-0260838-A1 | Titanium, zirconium and hafnium enolates as initiators in the polymerization of acrylic monomers to \"living\" polymers | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-03-23 | — | — | EP | disclosed |
| US-4728706-A | Titanium, zirconium- and hafnium containing initiators in the polymerization of acrylic monomers to \"living\" polymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-03-01 | — | — | US | disclosed |
| US-4711942-A | FROM ACRYLIC OR MALEIMIDE MONOMER AND ORGANOSILICON,-TIN, OR -GERMANIUM INITIATOR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-12-08 | — | — | US | disclosed |
| US-4681918-A | ACRYLIC-TYPE OR MALEIMIDE MONOMERS; ORGANOSILICON, TIN OR GERMANIUM INITIATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-07-21 | — | — | US | disclosed |
| US-4581428-A | Process for preparing \"living\" polymers using tetracoordinate organosilicon, organotin or organogermanium polymerization initiator with bifluoride ion source co-catalyst | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-04-08 | — | — | US | disclosed |
| EP-0145263-A1 | Living polymers and process for their preparation | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-06-19 | — | — | EP | disclosed |
| US-4524196-A | Process for preparing \"living\" polymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-06-18 | — | — | US | disclosed |
| US-4508880-A | ACRYLIC OR MALEIMIDE MONOMERS WITH ORGANOSILICON, (-TIN, OR-GERMANIUM) INITIATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-04-02 | — | — | US | disclosed |