Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 1.00 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9814708 | 1.00 | P2RX7 (1.00) | P2RX7HTTALOX15MEN1KMT2A | |
| SCHEMBL27786434 | 0.78 | P2RX7 (0.63) | P2RX7HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9814514 | 0.77 | P2RX7 (0.62) | P2RX7MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL11605633 | 0.70 | P2RX7 (0.58) | P2RX7HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9468809 | 0.67 | P2RX7 (0.55) | P2RX7HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL458507 | 0.66 | P2RX7 (0.53) | P2RX7MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL1037429 | 0.66 | P2RX7 (0.53) | P2RX7HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18039129 | 0.66 | P2RX7 (0.53) | P2RX7MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL1752087 | 0.66 | P2RX7 (0.53) | P2RX7MEN1KMT2ARAB9AKDM4E | |
| SCHEMBL17279823 | 0.64 | KDM4E (0.56) | P2RX7HTTALOX15MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150984-B1 | 6-(SUBSTITUTED) METHYLENEPENICILLANIC AND 6-(SUBSTITUTED) HYDROXYMETHYLPENICILLANIC ACIDS AND DERIVATIVES THEREOF | PFIZER INC. (US) | 1991-09-11 | — | — | EP | disclosed |
| US-5015473-A | Beta-lactamase inhibitors | PFIZER INC. (US) | 1991-05-14 | — | — | US | disclosed |