Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LSS | P48449 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11696173 | 0.81 | P2RX7 (0.42) | P2RX7KDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL11691729 | 0.81 | P2RX7 (0.42) | P2RX7KDM4EHSD17B10ALDH1A1KMT2A | |
| SCHEMBL12442424 | 0.81 | P2RX7 (0.42) | P2RX7KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL11695053 | 0.81 | P2RX7 (0.46) | P2RX7KDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL5487008 | 0.81 | PKM (0.43) | P2RX7KDM4EHSD17B10ALDH1A1KMT2A | |
| SCHEMBL11766757 | 0.78 | HTT (0.47) | P2RX7KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL9814708 | 0.77 | P2RX7 (1.00) | P2RX7KDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL9814705 | 0.77 | P2RX7 (1.00) | P2RX7KDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL11542619 | 0.73 | KDM4E (0.46) | P2RX7KDM4EHPGDHSD17B10LSS | |
| SCHEMBL27786434 | 0.72 | P2RX7 (0.63) | P2RX7KDM4EHPGDHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106290206-A | A kind of new small molecule cyano group colorimetric and Fluorescence Increasing type probe | 新疆大学 | 2017-01-04 | — | — | CN | claimed |
| CN-106238096-A | A kind of preparation method that catalyst SBA-15@Schiff's base be can be recycled | 新疆大学 | 2016-12-21 | — | — | CN | claimed |
| US-4017509-A | OXIDATION OF CORRESPONDING ALCOHOL | MITSUI TOATSU CHEMICALS, INCORPORATED (JA) | 1977-04-12 | — | — | US | claimed |
| JP-52078873-A | — | — | None | — | — | JP | disclosed |
| CN-117642404-A | Small molecule modulators of glucocerebrosidase activity and uses thereof | 凡况生化公司 | 2024-03-01 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-111233850-B | Naphthol derivative containing benzothiazole amino and heteroaryl and preparation method and application thereof | 南开大学 | 2022-09-23 | — | — | CN | disclosed |
| US-20220259212-A1 | INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND/OR TRYPTOPHAN 2,3-DIOXYGENASE | IDORSIA PHARMACEUTICALS LTD (CH) | 2022-08-18 | — | — | US | disclosed |
| CN-114127066-A | Inhibitors of indoleamine 2, 3-dioxygenase and/or tryptophan 2, 3-dioxygenase | 爱杜西亚药品有限公司 | 2022-03-01 | — | — | CN | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3226858-B1 | IMIDAZOLE-BASED ANTIMICROBIAL AGENTS | PROCOMCURE BIOTECH GMBH (AT) | 2021-02-03 | — | — | EP | disclosed |
| EP-0007672-A1 | Isocyanoalkenes, process and useful intermediates for their preparation, pharmaceutical and fungicidal preparations containing those isocyanoalkenes and the use of the fungicidal preparations in agriculture | GIST-BROCADES N.V. (NL) | 1980-02-06 | — | — | EP | disclosed |
| JP-S5278873-A | PREPARATION OF 2-ARYL-1,2,3-TRIAZOLYL-4-ACETIC ACIDS | MITSUI TOATSU CHEM INC | 1977-07-02 | — | — | JP | disclosed |
| US-4032503-A | TRIAZOLE RING | CIBA-GEIGY CORPORATION (US) | 1977-06-28 | — | — | US | disclosed |
| US-4022772-A | OPTICAL BRIGHTENING | CIBA-GEIGY CORPORATION (US) | 1977-05-10 | — | — | US | disclosed |
| US-4017509-A | OXIDATION OF CORRESPONDING ALCOHOL | MITSUI TOATSU CHEMICALS, INCORPORATED (JA) | 1977-04-12 | — | — | US | disclosed |
| US-4017509-A | OXIDATION OF CORRESPONDING ALCOHOL | MITSUI TOATSU CHEMICALS, INCORPORATED (JA) | 1977-04-12 | — | — | US | disclosed |
| US-4017509-A | OXIDATION OF CORRESPONDING ALCOHOL | MITSUI TOATSU CHEMICALS, INCORPORATED (JA) | 1977-04-12 | — | — | US | disclosed |
| US-3966678-A | Maleic anhydride-polyaldimine prepolymers | RHONE-POULENC S.A. (FR) | 1976-06-29 | — | — | US | disclosed |
| US-3940388-A | OPTICAL BRIGHTENERS | SANDOZ LTD., (SANDOZ AG) (CH) | 1976-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220259212-A1 | INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND/OR TRYPTOPHAN 2,3-DIOXYGENASE | IDO2, TDO2, IDO1 | P2RX7 3759/4885KDM4E 1330/4885HPGD 95/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.