Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.32 |
| ▸ | GABRD | O14764 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.32 |
| ▸ | GABRE | P78334 | 2/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.32 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9814840 | 0.79 | ALDH1A1 (0.39) | CYP1A2MEN1ALDH1A1THRBKMT2A | |
| SCHEMBL9814657 | 0.76 | NAALAD2 (0.40) | CYP1A2MEN1ALDH1A1THRBKMT2A | |
| SCHEMBL9814922 | 0.76 | KMT2A (0.41) | CYP1A2MEN1ALDH1A1THRBKMT2A | |
| SCHEMBL9814772 | 0.74 | FFAR3 (0.43) | CYP1A2MEN1ALDH1A1THRBKMT2A | |
| SCHEMBL4810549 | 0.72 | LMNA (0.47) | CYP1A2MEN1ALDH1A1THRBKMT2A | |
| SCHEMBL6883490 | 0.71 | MEN1 (0.42) | CYP1A2MEN1ALDH1A1THRBKMT2A | |
| SCHEMBL11305844 | 0.69 | ALDH1A1 (0.56) | CYP1A2MEN1ALDH1A1THRBKMT2A | |
| SCHEMBL8856972 | 0.69 | ALDH1A1 (0.45) | CYP1A2MEN1ALDH1A1THRBKMT2A | |
| SCHEMBL28998763 | 0.68 | CYP1A2 (0.34) | CYP1A2MEN1ALDH1A1THRBKMT2A | |
| SCHEMBL28998764 | 0.68 | CYP1A2 (0.34) | CYP1A2MEN1ALDH1A1THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4927966-A | ANTITUMOR | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1990-05-22 | — | — | US | claimed |
| US-5010103-A | Anticarcinogenic agents | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF N.Y. (US) | 1991-04-23 | — | — | US | disclosed |
| US-4927966-A | ANTITUMOR | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1990-05-22 | — | — | US | disclosed |