Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.32 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.32 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8856972 | 0.87 | ALDH1A1 (0.45) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| SCHEMBL1406211 | 0.82 | LMNA (0.46) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| SCHEMBL27614232 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| SCHEMBL9814922 | 0.80 | KMT2A (0.41) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| SCHEMBL9814657 | 0.80 | NAALAD2 (0.40) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| SCHEMBL9814772 | 0.79 | FFAR3 (0.43) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| SCHEMBL9814735 | 0.79 | CYP1A2 (0.36) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| SCHEMBL4810549 | 0.77 | LMNA (0.47) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| SCHEMBL11305844 | 0.73 | ALDH1A1 (0.56) | ALDH1A1MEN1CYP1A2THRBKMT2A | |
| SCHEMBL29271678 | 0.73 | ALDH1A1 (0.43) | ALDH1A1MEN1CYP1A2THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4927966-A | ANTITUMOR | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1990-05-22 | — | — | US | claimed |
| US-5010103-A | Anticarcinogenic agents | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF N.Y. (US) | 1991-04-23 | — | — | US | disclosed |
| US-4927966-A | ANTITUMOR | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1990-05-22 | — | — | US | disclosed |