Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 13/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.44 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.43 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9814843 | 0.81 | CPB2 (0.59) | FOLH1CYP1A2CPB2GRM3NAALAD2 | |
| SCHEMBL9814925 | 0.78 | FOLH1 (0.56) | FOLH1CPB2GRM3NAALAD2 | |
| SCHEMBL9814774 | 0.76 | FOLH1 (0.50) | FOLH1CPB2GRM3NAALAD2 | |
| SCHEMBL7613147 | 0.76 | FOLH1 (0.50) | FOLH1CYP1A2GRM3NAALAD2 | |
| SCHEMBL9814660 | 0.76 | FOLH1 (0.50) | FOLH1CPB2GRM3NAALAD2 | |
| SCHEMBL9814887 | 0.76 | FOLH1 (0.61) | FOLH1GRM3NAALAD2 | |
| SCHEMBL11433451 | 0.73 | CPB2 (0.54) | FOLH1CYP1A2CPB2 | |
| SCHEMBL108166 | 0.72 | FOLH1 (0.76) | FOLH1GRM3NAALAD2 | |
| SCHEMBL7611637 | 0.71 | FOLH1 (0.58) | FOLH1CYP1A2GRM3NAALAD2 | |
| SCHEMBL13726298 | 0.70 | FOLH1 (0.73) | FOLH1GRM3NAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4927966-A | ANTITUMOR | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1990-05-22 | — | — | US | claimed |
| US-5010103-A | Anticarcinogenic agents | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF N.Y. (US) | 1991-04-23 | — | — | US | disclosed |
| US-4927966-A | ANTITUMOR | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1990-05-22 | — | — | US | disclosed |