Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 7/20 | 0.72 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | ELANE | P08246 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7929154 | 0.96 | SRD5A2 (0.67) | SRD5A2PARP10POLBBCL2L1MCL1 | |
| SCHEMBL15448720 | 0.92 | SRD5A2 (0.59) | SRD5A2PARP10POLBALDH1A1NPSR1 | |
| SCHEMBL2862520 | 0.92 | SRD5A2 (0.59) | SRD5A2PARP10POLBALDH1A1NPSR1 | |
| SCHEMBL3020544 | 0.92 | SRD5A2 (0.59) | SRD5A2PARP10POLBALDH1A1NPSR1 | |
| SCHEMBL28319232 | 0.92 | SRD5A2 (0.59) | SRD5A2PARP10POLBALDH1A1NPSR1 | |
| SCHEMBL9536469 | 0.90 | SRD5A2 (0.88) | SRD5A2PARP10POLBELANEALDH1A1 | |
| SCHEMBL13599782 | 0.90 | SRD5A2 (0.88) | SRD5A2PARP10POLBELANEALDH1A1 | |
| SCHEMBL1082112 | 0.90 | SRD5A2 (0.88) | SRD5A2PARP10POLBELANEALDH1A1 | |
| SCHEMBL235530 | 0.90 | SRD5A2 (0.88) | SRD5A2PARP10POLBELANEALDH1A1 | |
| SCHEMBL2866068 | 0.90 | SRD5A2 (0.88) | SRD5A2PARP10POLBELANEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262919-B1 | PREPARATION OF ARYL CARBONYL COMPOUNDS | RAYCHEM LIMITED (GB) | 1991-09-11 | — | — | EP | disclosed |
| US-4898983-A | FRIEDEL-CRAFTS PROCESS; LEWIS ACIDS, BY-PRODUCT INHIBITION; ACID HALIDES, ACTIVE HYDROGEN AROMATIC COMPONENTS; CONTROLLING AGENTS | RAYCHEM LIMITED (GB) | 1990-02-06 | — | — | US | disclosed |
| EP-0262919-A2 | Preparation of aryl carbonyl compounds | RAYCHEM LIMITED (GB) | 1988-04-06 | — | — | EP | disclosed |