Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 4/20 | 0.59 |
| ▸ | LTA4H | P09960 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.52 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.52 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.52 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.52 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15448720 | 1.00 | SRD5A2 (0.59) | SRD5A2LTA4HCES2CES1ALDH1A1 | |
| SCHEMBL2862520 | 1.00 | SRD5A2 (0.59) | SRD5A2LTA4HCES2CES1ALDH1A1 | |
| SCHEMBL28319232 | 1.00 | SRD5A2 (0.59) | SRD5A2LTA4HCES2CES1ALDH1A1 | |
| SCHEMBL27605858 | 0.94 | SRD5A2 (0.53) | SRD5A2LTA4HCES2CES1ALDH1A1 | |
| SCHEMBL17668667 | 0.94 | BCL2L1 (0.55) | SRD5A2LTA4HCES2CES1ALDH1A1 | |
| SCHEMBL2188901 | 0.92 | PARP10 (0.58) | SRD5A2LTA4HALDH1A1MAPTHPGD | |
| SCHEMBL7929154 | 0.92 | SRD5A2 (0.67) | SRD5A2ALDH1A1HPGDPARP10LMNA | |
| SCHEMBL9814841 | 0.92 | SRD5A2 (0.72) | SRD5A2LTA4HALDH1A1HPGDPARP10 | |
| SCHEMBL18657389 | 0.90 | SRD5A2 (0.50) | SRD5A2LTA4HCES2CES1ALDH1A1 | |
| SCHEMBL9777083 | 0.90 | HPGD (0.59) | SRD5A2LTA4HALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2937374-B1 | METHOD FOR PRODUCING CYCLIC POLYPHENYLENE ETHER ETHER KETONE COMPOSITION AND LINEAR POLYPHENYLENE ETHER ETHER KETONE, AND METHOD FOR PRODUCING POLYPHENYLENE ETHER ETHER KETONE | TORAY INDUSTRIES (JP) | 2018-06-27 | — | — | EP | disclosed |
| US-9765185-B2 | High purity diphenyl sulfone, preparation and use thereof for the preparation of a poly(aryletherketone) | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2017-09-19 | — | — | US | disclosed |
| US-9765185-B2 | High purity diphenyl sulfone, preparation and use thereof for the preparation of a poly(aryletherketone) | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2017-09-19 | — | — | US | disclosed |
| US-20150344418-A1 | HIGH PURITY DIPHENYL SULFONE, PREPARATION AND USE THEREOF FOR THE PREPARATION OF A POLY(ARYLETHERKETONE) | SOLVAY ADVANCED POLYMERS, LLC (US) | 2015-12-03 | — | — | US | disclosed |
| US-20150344418-A1 | HIGH PURITY DIPHENYL SULFONE, PREPARATION AND USE THEREOF FOR THE PREPARATION OF A POLY(ARYLETHERKETONE) | SOLVAY ADVANCED POLYMERS, LLC (US) | 2015-12-03 | — | — | US | disclosed |
| US-9133111-B2 | High purity diphenyl sulfone, preparation and use thereof for the preparation of a poly(aryletherketone) | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2015-09-15 | — | — | US | disclosed |
| US-9133111-B2 | High purity diphenyl sulfone, preparation and use thereof for the preparation of a poly(aryletherketone) | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2015-09-15 | — | — | US | disclosed |
| US-8987406-B2 | Cyclic polyphenylene ether ether ketone composition and method for producing the same | TORAY INDUSTRIES, INC. (JP) | 2015-03-24 | — | — | US | disclosed |
| US-8987406-B2 | Cyclic polyphenylene ether ether ketone composition and method for producing the same | TORAY INDUSTRIES, INC. (JP) | 2015-03-24 | — | — | US | disclosed |
| US-8981035-B2 | Production method of poly (phenylene ether ether ketone) | TORAY INDUSTRIES, INC. (JP) | 2015-03-17 | — | — | US | disclosed |
| EP-1640067-B1 | Method for preparing aromatic polyethers using phosphazenium salt phase transfer catalysts | SABIC INNOVATIVE PLASTICS IP (NL) | 2013-07-17 | — | — | EP | disclosed |
| US-20120259086-A1 | CYCLIC POLYPHENYLENE ETHER ETHER KETONE COMPOSITION AND METHOD FOR PRODUCING THE SAME | TORAY INDUSTRIES, INC. (JP) | 2012-10-11 | — | — | US | disclosed |
| US-20120259086-A1 | CYCLIC POLYPHENYLENE ETHER ETHER KETONE COMPOSITION AND METHOD FOR PRODUCING THE SAME | TORAY INDUSTRIES, INC. (JP) | 2012-10-11 | — | — | US | disclosed |
| US-20110201775-A1 | High purity diphenyl sulfone, preparation and use thereof for the preparation of a poly(aryletherketone) | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2011-08-18 | — | — | US | disclosed |
| US-20110201775-A1 | High purity diphenyl sulfone, preparation and use thereof for the preparation of a poly(aryletherketone) | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2011-08-18 | — | — | US | disclosed |
| US-20100204431-A1 | METHOD OF MAKING AN AROMATIC POLYETHER COMPOSITION USING PHOSPHAZENIUM SALT PHASE TRANSFER CATALYSTS | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-08-12 | — | — | US | disclosed |
| US-7705190-B2 | phosphazenium salt phase transfer catalysts are shown to be especially useful in the preparation of aromatic polyethers such as polyether sulfones; enhanced stability | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-04-27 | — | — | US | disclosed |
| US-20070112223-A1 | phosphazenium salt phase transfer catalysts are shown to be especially useful in the preparation of aromatic polyethers such as polyether sulfones; enhanced stability | GENERAL ELECTRIC COMPANY (US) | 2007-05-17 | — | — | US | disclosed |
| US-20060069291-A1 | Phosphazenium salt phase transfer catalysts | GENERAL ELECTRIC COMPANY | 2006-03-30 | — | — | US | disclosed |
| EP-1640067-A2 | Phosphazenium salt phase transfer catalysts | GENERAL ELECTRIC COMPANY (US) | 2006-03-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201775-A1 | High purity diphenyl sulfone, preparation and use thereof for the preparation of a poly(aryletherketone) | DHPS, PKM, PCBP1 | SRD5A2 1673/4885LTA4H 3193/4885CES2 4114/4885 |
| US-20070112223-A1 | phosphazenium salt phase transfer catalysts are shown to be especially useful in the preparation of aromatic polyethers such as polyether sulfones; enhanced stability | PHOSPHO1, MPST, PGLS | SRD5A2 2360/4885LTA4H 3819/4885CES2 1848/4885 |
| US-20060069291-A1 | Phosphazenium salt phase transfer catalysts | PHOSPHO1, MPST, PAPSS1 | SRD5A2 2775/4885LTA4H 3728/4885CES2 1388/4885 |
| US-20150344418-A1 | HIGH PURITY DIPHENYL SULFONE, PREPARATION AND USE THEREOF FOR THE PREPARATION OF A POLY(ARYLETHERKETONE) | DHPS, PKM, PCBP1 | SRD5A2 1914/4885LTA4H 3306/4885CES2 4056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.