SCHEMBL2862520

SCHEMBL2862520

O=C(c1ccc(F)cc1)c1ccc(Oc2ccc(C(=O)c3ccc(F)cc3)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 4/20 0.59
LTA4H P09960 1/20 0.57
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
ALDH1A1 P00352 3/20 0.52
MAPT P10636 2/20 0.52
HPGD P15428 2/20 0.52
RAB9A P51151 2/20 0.52
KMT2A Q03164 1/20 0.52
PARP15 Q460N3 1/20 0.52
PARP14 Q460N5 1/20 0.52
PARP10 Q53GL7 1/20 0.52
PARP16 Q8N5Y8 1/20 0.52
PARP11 Q9NR21 1/20 0.52
PARP4 Q9UKK3 1/20 0.52
LMNA P02545 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
CYP3A4 P08684 1/20 0.49
MAPK14 Q16539 1/20 0.49
POLB P06746 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15448720 1.00 SRD5A2 (0.59) SRD5A2LTA4HCES2CES1ALDH1A1
SCHEMBL3020544 1.00 SRD5A2 (0.59) SRD5A2LTA4HCES2CES1ALDH1A1
SCHEMBL28319232 1.00 SRD5A2 (0.59) SRD5A2LTA4HCES2CES1ALDH1A1
SCHEMBL27605858 0.94 SRD5A2 (0.53) SRD5A2LTA4HCES2CES1ALDH1A1
SCHEMBL17668667 0.94 BCL2L1 (0.55) SRD5A2LTA4HCES2CES1ALDH1A1
SCHEMBL2188901 0.92 PARP10 (0.58) SRD5A2LTA4HALDH1A1MAPTHPGD
SCHEMBL7929154 0.92 SRD5A2 (0.67) SRD5A2ALDH1A1HPGDPARP10LMNA
SCHEMBL9814841 0.92 SRD5A2 (0.72) SRD5A2LTA4HALDH1A1HPGDPARP10
SCHEMBL18657389 0.90 SRD5A2 (0.50) SRD5A2LTA4HCES2CES1ALDH1A1
SCHEMBL9777083 0.90 HPGD (0.59) SRD5A2LTA4HALDH1A1HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4731429-A Novel poly(aryl ether ketones) AMOCO CORPORATION (US) 1988-03-15 US claimed
EP-0229777-A1 NOVEL POLY(ARYL ETHER KETONES) AMOCO CORPORATION (US) 1987-07-29 EP claimed
WO-1986007599-A1 NOVEL POLY(ARYL ETHER KETONES) AMOCO CORPORATION (US) 1986-12-31 WO claimed
CN-118325068-A Multielement copolymerization end-capped polyether ketone and preparation method thereof 吉林大学 2024-07-12 CN disclosed
CN-118085286-A Polyarylether electrochromic polymer and preparation method and application thereof 吉林大学 2024-05-28 CN disclosed
US-9765185-B2 High purity diphenyl sulfone, preparation and use thereof for the preparation of a poly(aryletherketone) SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2017-09-19 US disclosed
US-9765185-B2 High purity diphenyl sulfone, preparation and use thereof for the preparation of a poly(aryletherketone) SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2017-09-19 US disclosed
EP-2690122-B1 AROMATIC SULFONIC ACID DERIVATIVE, SULFONIC ACID GROUP-CONTAINING POLYMER, BLOCK COPOLYMER, POLYMER ELECTROLYTE MATERIAL, POLYMER ELECTROLYTE FORM ARTICLE, AND POLYMER ELECTROLYTE FUEL CELL TORAY INDUSTRIES (JP) 2017-03-29 EP disclosed
US-9553326-B2 Aromatic sulfonic acid derivative, sulfonic acid group-containing polymer, block copolymer, polymer electrolyte material, polymer electrolyte form article, and polymer electrolyte fuel cell TORAY INDUSTRIES, INC. (JP) 2017-01-24 US disclosed
US-9553326-B2 Aromatic sulfonic acid derivative, sulfonic acid group-containing polymer, block copolymer, polymer electrolyte material, polymer electrolyte form article, and polymer electrolyte fuel cell TORAY INDUSTRIES, INC. (JP) 2017-01-24 US disclosed
US-20150380759-A1 AROMATIC SULFONIC ACID DERIVATIVE, SULFONIC ACID GROUP-CONTAINING POLYMER, BLOCK COPOLYMER, POLYMER ELECTROLYTE MATERIAL, POLYMER ELECTROLYTE FORM ARTICLE, AND POLYMER ELECTROLYTE FUEL CELL TORAY INDUSTRIES, INC. 2015-12-31 US disclosed
US-4774296-A Block polymers containing a poly(aryl ether ketone) and methods for their production AMOCO CORPORATION (US) 1988-09-27 US disclosed
US-4767837-A Method for preparing poly(aryl ether ketones) RAYCHEM CORPORATION (US) 1988-08-30 US disclosed
EP-0275035-A2 Process for the preparation of poly(aryl ether ketones) BASF Aktiengesellschaft (DE) 1988-07-20 EP disclosed
EP-0268112-A2 A novel aromatic polyether and a process for producing a polyether Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1988-05-25 EP disclosed
EP-0262919-A2 Preparation of aryl carbonyl compounds RAYCHEM LIMITED (GB) 1988-04-06 EP disclosed
EP-0221149-A1 BLOCK POLYMERS CONTAINING A POLY(ARYL ETHER KETONE) AND METHODS FOR THEIR PRODUCTION AMOCO CORPORATION (US) 1987-05-13 EP disclosed
WO-1986006389-A1 BLOCK POLYMERS CONTAINING A POLY(ARYL ETHER KETONE) AND METHODS FOR THEIR PRODUCTION AMOCO CORPORATION (US) 1986-11-06 WO disclosed
EP-0178184-A1 Preparation of aromatic carbonyl compounds RAYCHEM CORPORATION (a Delaware corporation) (US) 1986-04-16 EP disclosed
EP-0135130-A2 Process for the preparation of polyethers BASF Aktiengesellschaft (DE) 1985-03-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150380759-A1 AROMATIC SULFONIC ACID DERIVATIVE, SULFONIC ACID GROUP-CONTAINING POLYMER, BLOCK COPOLYMER, POLYMER ELECTROLYTE MATERIAL, POLYMER ELECTROLYTE FORM ARTICLE, AND POLYMER ELECTROLYTE FUEL CELL PAH, SMCHD1, ASIC1 SRD5A2 1422/4885LTA4H 3720/4885CES2 2346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.