Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SNCA | P37840 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9798455 | 0.83 | MAPT (0.51) | MAPTSMN1; SMN2NPC1L3MBTL1RAB9A | |
| SCHEMBL9798425 | 0.83 | MAPT (0.51) | MAPTSMN1; SMN2NPC1L3MBTL1RAB9A | |
| SCHEMBL9798431 | 0.83 | MAPT (0.51) | MAPTSMN1; SMN2NPC1L3MBTL1RAB9A | |
| SCHEMBL9798449 | 0.83 | MAPT (0.51) | MAPTSMN1; SMN2NPC1L3MBTL1RAB9A | |
| SCHEMBL9799223 | 0.76 | MEN1 (0.53) | MAPTL3MBTL1SNCAMEN1KMT2A | |
| SCHEMBL9798764 | 0.74 | ALDH3A1 (0.46) | MAPTNPC1RAB9ASNCAMEN1 | |
| SCHEMBL9798595 | 0.73 | MEN1 (0.50) | MAPTL3MBTL1SNCAMEN1KMT2A | |
| SCHEMBL9798589 | 0.73 | MEN1 (0.50) | MAPTL3MBTL1SNCAMEN1KMT2A | |
| SCHEMBL9814655 | 0.72 | ALDH1A1 (0.38) | MAPTRAB9ASNCAMEN1KMT2A | |
| SCHEMBL9798663 | 0.72 | ALDH1A1 (0.38) | MAPTRAB9ASNCAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438557-A1 | NON-LINEAR OPTICALLY ACTIVE POLYIMIDES | MERCK PATENT GmbH (DE) | 1991-07-31 | — | — | EP | disclosed |
| WO-1991003001-A1 | NON-LINEAR OPTICALLY ACTIVE POLYIMIDES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-03-07 | — | — | WO | disclosed |