SCHEMBL9814882

SCHEMBL9814882

Cc1ccc(N(C)C)c(N(C)C)c1C

nearest known ligand 0.31

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 1/20 0.31
NEK2 P51955 1/20 0.31
LIMK1 P53667 1/20 0.31
DYRK1A Q13627 1/20 0.31
CLK4 Q9HAZ1 1/20 0.31
KDM4E B2RXH2 2/20 0.31
GAA P10253 2/20 0.31
MAPT P10636 2/20 0.31
EP300 Q09472 1/20 0.30
KAT2B Q92831 1/20 0.30
KAT8 Q9H7Z6 1/20 0.30
KMT2A Q03164 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2A6 P11509 1/20 0.30
TSHR P16473 1/20 0.30
TDP2 O95551 1/20 0.30
NSD2 O96028 1/20 0.30
HSP90AA1 P07900 1/20 0.30
PAX8 Q06710 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21173492 0.84 MAPT (0.33) CHEK1NEK2LIMK1DYRK1ACLK4
SCHEMBL11789041 0.82 CHEK1 (0.32) CHEK1NEK2LIMK1DYRK1ACLK4
SCHEMBL24611287 0.81 TSHR (0.33) CYP1A2CYP2A6TSHRTDP2NSD2
SCHEMBL392464 0.79 GAA (0.33) CHEK1NEK2LIMK1DYRK1ACLK4
SCHEMBL9757011 0.78 GAA (0.39) CHEK1NEK2LIMK1DYRK1ACLK4
SCHEMBL990388 0.76 EP300 (0.45) KDM4EGAAMAPTEP300KAT2B
SCHEMBL7902639 0.76
SCHEMBL15732352 0.75
SCHEMBL3965959 0.73 TRPA1 (0.41) KDM4EMAPTEP300KAT2BKAT8
SCHEMBL27649636 0.73 CHEK1 (0.30) CHEK1NEK2LIMK1DYRK1ACLK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114341131-A Novel oxadiazole compounds comprising a 5-membered heteroaromatic ring for controlling or preventing phytopathogenic fungi PI工业有限公司 2022-04-12 CN disclosed
CN-113454063-A 3-substituted phenylamidine compounds, preparation method and application thereof PI工业有限公司 2021-09-28 CN disclosed
CN-113195461-A Novel oxadiazole compound PI工业有限公司 2021-07-30 CN disclosed
CN-113195483-A Novel oxadiazole compound PI工业有限公司 2021-07-30 CN disclosed
CN-112004813-A Oxadiazole compounds for controlling phytopathogenic fungi PI工业有限公司 2020-11-27 CN disclosed
CN-111936485-A Novel anthranilamides, their use as pesticides and process for their preparation PI工业有限公司 2020-11-13 CN disclosed
CN-111670186-A Pyrazolopyridine-diamides, their use as pesticides and processes for their preparation PI工业有限公司 2020-09-15 CN disclosed
EP-0143582-B1 BIPOLAR MEMBRANES Chinese Petroleum Corporation (TW) 1991-09-04 EP disclosed
US-4673454-A Process for preparing bipolar membranes CHINESE PETROLEUM CORP. (TW) 1987-06-16 US disclosed
US-4584246-A Bipolar membranes CHINESE PETROLEUM CORP. (TW) 1986-04-22 US disclosed
EP-0143582-A2 Bipolar membranes Chinese Petroleum Corporation (TW) 1985-06-05 EP disclosed
US-4116889-A Bipolar membranes and method of making same ALLIED CHEMICAL CORPORATION (US) 1978-09-26 US disclosed