SCHEMBL990388

SCHEMBL990388

Cc1c(O)ccc(N(C)C)c1N(C)C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.45
KAT2B Q92831 1/20 0.45
KAT8 Q9H7Z6 1/20 0.45
ESR1 P03372 1/20 0.39
APP P05067 7/20 0.36
TRPA1 O75762 2/20 0.34
ATM Q13315 1/20 0.34
TYR P14679 1/20 0.32
PIM1 P11309 1/20 0.31
MAPT P10636 3/20 0.31
GAA P10253 2/20 0.31
MAPK1 P28482 2/20 0.31
ALDH1A1 P00352 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
MEN1 O00255 1/20 0.31
RGS12 O14924 1/20 0.31
USP2 O75604 1/20 0.31
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132669 0.81 EP300 (0.48) EP300KAT2BKAT8ESR1APP
SCHEMBL21173492 0.80 MAPT (0.33) EP300KAT2BKAT8MAPTGAA
SCHEMBL10929723 0.79 TRPA1 (0.41) EP300KAT2BKAT8ESR1TRPA1
SCHEMBL9814882 0.76 CHEK1 (0.31) EP300KAT2BKAT8ESR1MAPT
SCHEMBL11015061 0.76 EP300 (0.44) EP300KAT2BKAT8ESR1APP
SCHEMBL27667634 0.76 TRPA1 (0.34) EP300KAT2BKAT8ESR1TRPA1
SCHEMBL8762568 0.74 EP300 (0.47) EP300KAT2BKAT8ESR1APP
SCHEMBL9757011 0.74 GAA (0.39) EP300KAT2BKAT8APPMAPT
SCHEMBL7902639 0.73
SCHEMBL4028857 0.73 ACHE (0.39) EP300KAT2BKAT8ESR1APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102439056-B Protein-containing emulsions and adhesives, and their manufacture and use Biopolymer Technology Co.,Ltd. (IL) 2016-01-13 CN claimed
CN-102439056-A Protein-containing emulsions and adhesives, and their manufacture and use BIOPOLYMER TECHNOLOGIES LTD 2012-05-02 CN claimed
CN-105585996-B Lotion and adhesive and their manufacture and purposes containing albumen 爱福特立 2019-04-05 CN disclosed
CN-103819657-B Benzylated polyalkylene polyamines and uses thereof 气体产品与化学公司 2017-04-12 CN disclosed
CN-105585996-A Protein-containing emulsions and adhesives, and manufacture and use thereof BIOPOLYMER TECH LTD 2016-05-18 CN disclosed
CN-102439056-B Protein-containing emulsions and adhesives, and their manufacture and use Biopolymer Technology Co.,Ltd. (IL) 2016-01-13 CN disclosed
CN-102439058-B Foam materials containing albumen, their manufacture and purposes Biopolymer Technology Co.,Ltd. (IL) 2015-07-29 CN disclosed
CN-101643538-B Benzylated aminopropylated ethylenediamines and uses thereof AIR PROD & CHEM 2013-06-19 CN disclosed
EP-2454304-A2 FORMAMIDE-CONTAINING REACTIVE SYSTEMS Bayer MaterialScience AG (DE) 2012-05-23 EP disclosed
CN-102439058-A Protein-containing foams, manufacture and use thereof BIOPOLYMER TECHNOLOGIES LTD 2012-05-02 CN disclosed
CN-102439056-A Protein-containing emulsions and adhesives, and their manufacture and use BIOPOLYMER TECHNOLOGIES LTD 2012-05-02 CN disclosed
WO-2011006607-A2 FORMAMIDE-CONTAINING REACTIVE SYSTEMS BAYER MATERIALSCIENCE AG (DE) 2011-01-20 WO disclosed
CN-101643538-A Benzylated aminopropylated ethylenediamines and uses thereof AIR PROD & CHEM 2010-02-10 CN disclosed
CN-1284814-C Double-compounet foam system for making building foam body and its application HILTI AG (LI) 2006-11-15 CN disclosed
US-20040138402-A1 Two component polyurethane adhesive for wooden materials HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2004-07-15 US disclosed
CN-1495213-A Double-compounet foam system for making building foam body and its application ϣ���ٹɷݹ�˾ 2004-05-12 CN disclosed