Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 10/20 | 0.41 |
| ▸ | MMP2 | P08253 | 7/20 | 0.41 |
| ▸ | MMP13 | P45452 | 4/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9814920 | 0.84 | MMP2 (0.48) | MMP9MMP2MMP13MMP3KDM4E | |
| SCHEMBL9814969 | 0.82 | NPC1 (0.52) | MMP9MMP2MMP13MMP3MMP1 | |
| SCHEMBL10420790 | 0.80 | MMP2 (0.50) | MMP9MMP2MMP13MMP3ADAM17 | |
| SCHEMBL10419243 | 0.80 | MMP2 (0.50) | MMP9MMP2MMP13MMP3ADAM17 | |
| SCHEMBL10419718 | 0.80 | MMP2 (0.50) | MMP9MMP2MMP13MMP3ADAM17 | |
| SCHEMBL10420376 | 0.79 | MMP2 (0.51) | MMP9MMP2MMP13MMP3MMP1 | |
| SCHEMBL10420440 | 0.78 | MMP2 (0.54) | MMP9MMP2MMP13MMP3MMP1 | |
| SCHEMBL10420884 | 0.78 | MMP2 (0.54) | MMP9MMP2MMP13MMP3MMP1 | |
| SCHEMBL10419465 | 0.78 | MMP2 (0.54) | MMP9MMP2MMP13MMP3MMP1 | |
| SCHEMBL7825144 | 0.78 | MMP9 (0.55) | MMP9MMP2MMP13MMP3ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0275024-B1 | CARBOXYLIC-ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1991-09-04 | — | — | EP | disclosed |
| US-4833161-A | ANTIDIABETIC AGENTS, ANTICHOLESTEROL AGENTS, ANTILIPEMIC AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-05-23 | — | — | US | disclosed |
| EP-0275024-A1 | Carboxylic-acid derivatives, processes for their preparation and medicaments containing these compounds | Roche Diagnostics GmbH (DE) | 1988-07-20 | — | — | EP | disclosed |