Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPRB | P23467 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CFD | P00746 | 1/20 | 0.42 |
| ▸ | F11 | P03951 | 1/20 | 0.42 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6254995 | 0.86 | PTGER1 (0.48) | PTGER1 | |
| SCHEMBL916790 | 0.84 | L3MBTL1 (0.39) | PTK2BBRD4MAPTL3MBTL1HPGD | |
| SCHEMBL914481 | 0.84 | L3MBTL1 (0.42) | PTK2BBRD4MAPTL3MBTL1HPGD | |
| SCHEMBL9171630 | 0.82 | ALPG (0.36) | GAAALPGPTK2BMMEACE | |
| SCHEMBL1407856 | 0.81 | TRPA1 (0.42) | HPGDMEN1KMT2ACETP | |
| SCHEMBL1011308 | 0.79 | MME (0.49) | MMEACECPA1ACE2PTPN2 | |
| SCHEMBL916315 | 0.78 | TSHR (0.49) | GAAHTR1AMEN1KMT2AMAPK1 | |
| SCHEMBL916701 | 0.77 | KDM4E (0.36) | HPGDKDM4EALDH1A1LMNA | |
| SCHEMBL915190 | 0.76 | FOLH1 (0.40) | TDP1HPGDKDM4EMEN1ALDH1A1 | |
| SCHEMBL2008230 | 0.76 | EPHX2 (0.36) | HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295729-B1 | INTRAMOLECULAR NUCLEOPHILIC DISPLACEMENT COMPOUND AND USE IN PHOTOGRAPHY | AGFA-GEVAERT N.V. (BE) | 1991-09-04 | — | — | EP | disclosed |
| US-4912028-A | Alkali permeable hydrophilic colloid | AGFA-GEVAERT, N.V. (BE) | 1990-03-27 | — | — | US | disclosed |
| EP-0295729-A1 | Intramolecular nucleophilic displacement compound and use in photography | AGFA-GEVAERT N.V. (BE) | 1988-12-21 | — | — | EP | disclosed |