Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9814951 | 0.88 | HTR1A (0.51) | GAAHTR1ADRD2ALPGPTK2B | |
| SCHEMBL9815055 | 0.78 | GAA (0.49) | GAAHTR1ADRD2ALPGPTK2B | |
| SCHEMBL6254663 | 0.74 | PTGER1 (0.51) | PTGER1MEN1KMT2A | |
| SCHEMBL9169993 | 0.73 | HTR1A (0.40) | GAAHTR1ADRD2ALPGPTK2B | |
| SCHEMBL9814998 | 0.72 | DRD2 (0.54) | GAAHTR1ADRD2ALPGPTK2B | |
| SCHEMBL1894256 | 0.72 | HTR1A (0.67) | GAAHTR1ADRD2ALPGPTK2B | |
| SCHEMBL27684390 | 0.71 | APP (0.39) | GAAALPGPTK2BABCB1APP | |
| SCHEMBL19986739 | 0.71 | MRGPRX4 (0.44) | GAAHTR1ADRD2ALPGPTK2B | |
| SCHEMBL914480 | 0.71 | L3MBTL1 (0.53) | MAPTL3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL27714342 | 0.70 | HTR1A (0.65) | GAAHTR1ADRD2ALPGPTK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295729-B1 | INTRAMOLECULAR NUCLEOPHILIC DISPLACEMENT COMPOUND AND USE IN PHOTOGRAPHY | AGFA-GEVAERT N.V. (BE) | 1991-09-04 | — | — | EP | disclosed |
| US-4912028-A | Alkali permeable hydrophilic colloid | AGFA-GEVAERT, N.V. (BE) | 1990-03-27 | — | — | US | disclosed |
| EP-0295729-A1 | Intramolecular nucleophilic displacement compound and use in photography | AGFA-GEVAERT N.V. (BE) | 1988-12-21 | — | — | EP | disclosed |