Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.60 |
| ▸ | CETP | P11597 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31091435 | 0.86 | EP300 (0.66) | EP300CETPNPC1LMNARAB9A | |
| SCHEMBL776355 | 0.86 | NPC1 (0.59) | EP300CETPNPC1LMNARAB9A | |
| SCHEMBL774893 | 0.86 | NPC1 (0.59) | EP300CETPNPC1LMNARAB9A | |
| SCHEMBL27476154 | 0.85 | ALDH1A1 (0.60) | EP300CETPNPC1LMNARAB9A | |
| SCHEMBL9815026 | 0.85 | ALDH1A1 (0.51) | SMN1; SMN2TSHRKDM4EALDH1A1GAA | |
| SCHEMBL776746 | 0.84 | LMNA (0.60) | EP300CETPNPC1LMNARAB9A | |
| SCHEMBL9395051 | 0.82 | CETP (0.77) | EP300CETPLMNASOAT1TSHR | |
| SCHEMBL5878480 | 0.82 | CETP (0.77) | EP300CETPLMNASOAT1TSHR | |
| SCHEMBL8613334 | 0.82 | HDAC1 (0.51) | NPC1LMNARAB9ASMN1; SMN2KDM4E | |
| SCHEMBL23048462 | 0.81 | CYP1A2 (0.67) | EP300CETPLMNATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447949-A1 | Optical oxygen sensor | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-25 | — | — | EP | claimed |
| EP-0447949-A1 | Optical oxygen sensor | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-25 | — | — | EP | disclosed |