Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | PER2 | O15055 | 4/20 | 0.38 |
| ▸ | CRY2 | Q49AN0 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | INMT | O95050 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL329869 | 0.87 | F2 (0.45) | L3MBTL1PER2CRY2F2ELANE | |
| SCHEMBL133648 | 0.87 | CYP2D6 (0.36) | L3MBTL1LMNAPOLBCYP2D6CYP2C9 | |
| SCHEMBL22604425 | 0.82 | PER2 (0.36) | L3MBTL1PER2CRY2F2ELANE | |
| SCHEMBL9814986 | 0.82 | L3MBTL1 (0.41) | L3MBTL1LMNAHTTPOLB | |
| SCHEMBL7148826 | 0.81 | GAA (0.46) | L3MBTL1F2ELANECTSGCTRC | |
| SCHEMBL10416543 | 0.77 | PER2 (0.42) | L3MBTL1PER2CRY2F2ELANE | |
| SCHEMBL472276 | 0.77 | TSHR (0.35) | L3MBTL1PER2POLBCYP2D6CYP2C9 | |
| SCHEMBL6365391 | 0.77 | PER2 (0.46) | L3MBTL1PER2CRY2F2ELANE | |
| SCHEMBL1196066 | 0.76 | — | — | |
| SCHEMBL10850820 | 0.76 | KMT2A (0.35) | L3MBTL1GAASMN1; SMN2LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4864026-A | Method of manufacturing N-alkyl-N'-methyl-alkyleneureas, particularly N,N'-d | HULS AKTIENGESELLSCHAFT (DE) | 1989-09-05 | — | — | US | claimed |
| EP-0280781-B1 | PROCESS FOR THE PREPARATION OF N-ALKYL-N'-METHYL-CYCLIC UREAS, ESPECIALLY N,N'-DIMETHYLCYCLIC UREAS | HÜLS AKTIENGESELLSCHAFT (DE) | 1991-09-18 | — | — | EP | disclosed |
| US-4864026-A | Method of manufacturing N-alkyl-N'-methyl-alkyleneureas, particularly N,N'-d | HULS AKTIENGESELLSCHAFT (DE) | 1989-09-05 | — | — | US | disclosed |
| EP-0280781-A1 | Process for the preparation of N-alkyl-N'-methyl-cyclic ureas, especially N,N'-dimethylcyclic ureas | HÜLS AKTIENGESELLSCHAFT (DE) | 1988-09-07 | — | — | EP | disclosed |