SCHEMBL472276

SCHEMBL472276

O=C1N(CO)CCCN1CO

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
PER2 O15055 1/20 0.33
PIK3CD O00329 1/20 0.32
KMT2A Q03164 2/20 0.31
GRIN2D O15399 1/20 0.31
GRIN3B O60391 1/20 0.31
GRIN1 Q05586 1/20 0.31
GRIN2A Q12879 1/20 0.31
GRIN2B Q13224 1/20 0.31
GRIN2C Q14957 1/20 0.31
GRIN3A Q8TCU5 1/20 0.31
POLB P06746 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL133648 0.88 CYP2D6 (0.36) KMT2APOLBCYP2D6CYP2C9CYP2C19
SCHEMBL9815041 0.79 DPP4 (0.33) POLB
SCHEMBL9815040 0.77 L3MBTL1 (0.40) PER2KMT2APOLBCYP2D6CYP2C9
SCHEMBL10850820 0.77 KMT2A (0.35) KMT2APOLBCYP2D6CYP2C9CYP2C19
SCHEMBL9930180 0.77
SCHEMBL477750 0.74
SCHEMBL4447573 0.74
SCHEMBL10868666 0.74 ALOX15 (0.33) KMT2APOLBCYP2D6CYP2C9CYP2C19
SCHEMBL9814986 0.74 L3MBTL1 (0.41) POLBL3MBTL1
SCHEMBL6365391 0.72 PER2 (0.46) PER2PIK3CDL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250075051-A1 PROCESS FOR RECYCLING CONTAMINATED POLYMERS ARKEMA FRANCE (FR) 2025-03-06 US claimed
EP-4457275-A1 PROCESS FOR RECYCLING CONTAMINATED POLYMERS ARKEMA FRANCE (FR) 2024-11-06 EP claimed
WO-2023126441-A1 PROCESS FOR RECYCLING CONTAMINATED POLYMERS ARKEMA FRANCE (FR) 2023-07-06 WO claimed
EP-4206267-A1 PROCESS FOR RECYCLING CONTAMINATED POLYMERS ARKEMA FRANCE (FR) 2023-07-05 EP claimed
US-20200138787-A1 COSMETIC PRESERVATIVES AS THERAPEUTIC CORNEOSCLERAL TISSUE CROSS-LINKING AGENTS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2020-05-07 US claimed
US-10292967-B2 Compositions comprising corneoscleral tissue cross-linking agents THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2019-05-21 US claimed
US-20190015388-A1 COMPOSITIONS COMPRISING CORNEOSCLERAL TISSUE CROSS-LINKING AGENTS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2019-01-17 US claimed
US-10105350-B2 Cosmetic preservatives as therapeutic corneoscleral tissue cross-linking agents THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2018-10-23 US claimed
US-20160374992-A1 COSMETIC PRESERVATIVES AS THERAPEUTIC CORNEOSCLERAL TISSUE CROSS-LINKING AGENTS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2016-12-29 US claimed
EP-2412733-B1 Polymer, chemically amplified negative resist composition, and patterning process SHINETSU CHEMICAL CO (JP) 2016-03-23 EP claimed
US-8470512-B2 Polymer, chemically amplified negative resist composition, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-06-25 US claimed
US-20120028190-A1 POLYMER, CHEMICALLY AMPLIFIED NEGATIVE RESIST COMPOSITION, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-02-02 US claimed
EP-2412733-A1 Polymer, chemically amplified negative resist composition, and patterning process Shin-Etsu Chemical Co., Ltd. (JP) 2012-02-01 EP claimed
US-20080187735-A1 Non-Woven Fabric and Food Casing Which is Produced Therefrom and Which is Based on Cellulose Hydrate KALLE GMBH (DE) 2008-08-07 US claimed
US-4864026-A Method of manufacturing N-alkyl-N'-methyl-alkyleneureas, particularly N,N'-d HULS AKTIENGESELLSCHAFT (DE) 1989-09-05 US claimed
US-4438189-A POLYUNSATURATED COMPOUND, CROSSLINKABLE EPOXY OR METHYLOL COMPOUND HOECHST AKTIENGESELLSCHAFT (DE) 1984-03-20 US claimed
US-20250163006-A1 New Coolants, and Preparations Containing Same SYMRISE AG (DE) 2025-05-22 US disclosed
CN-116130796-B Intrinsic safety efficient electrolyte for rechargeable zinc ion battery and preparation and application thereof 上海交通大学 2025-05-06 CN disclosed
EP-0028204-A2 Pre-extended etherified aminoplast resins, process for their preparation and their use in surface coatings CIBA-GEIGY AG (CH) 1981-05-06 EP disclosed
US-3983043-A Mixtures of methylolalkyl ureas and their butyl ethers BASF AKTIENGESELLSCHAFT (DT) 1976-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190015388-A1 COMPOSITIONS COMPRISING CORNEOSCLERAL TISSUE CROSS-LINKING AGENTS SMCHD1, ALDH1A2, CRYAB TSHR 3434/4885PER2 2002/4885PIK3CD 4322/4885
US-10105350-B2 Cosmetic preservatives as therapeutic corneoscleral tissue cross-linking agents COL1A1, COL14A1, COL2A1 TSHR 2745/4885PER2 1361/4885PIK3CD 4502/4885
US-20200138787-A1 COSMETIC PRESERVATIVES AS THERAPEUTIC CORNEOSCLERAL TISSUE CROSS-LINKING AGENTS ALDH1A2, FAAH, FAAH2 TSHR 2194/4885PER2 1374/4885PIK3CD 4497/4885
US-10292967-B2 Compositions comprising corneoscleral tissue cross-linking agents SMCHD1, ALDH1A2, CRYAB TSHR 3434/4885PER2 2002/4885PIK3CD 4322/4885
US-20160374992-A1 COSMETIC PRESERVATIVES AS THERAPEUTIC CORNEOSCLERAL TISSUE CROSS-LINKING AGENTS COL1A1, COL14A1, COL2A1 TSHR 2745/4885PER2 1361/4885PIK3CD 4502/4885
US-20250163006-A1 New Coolants, and Preparations Containing Same TTR, TAS2R5, TAS2R50 TSHR 2090/4885PER2 823/4885PIK3CD 2176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.