Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPRB | P23467 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9814964 | 0.91 | LMNA (0.39) | LMNACYP1A2CYP2D6TSHRTDP1 | |
| SCHEMBL9815070 | 0.88 | MEN1 (0.36) | LMNACYP1A2CYP2D6TSHRTDP1 | |
| SCHEMBL6254663 | 0.80 | PTGER1 (0.51) | MEN1KMT2APTGER1 | |
| SCHEMBL9814951 | 0.79 | HTR1A (0.51) | LMNATDP1MEN1ALDH1A1TP53 | |
| SCHEMBL27684390 | 0.77 | APP (0.39) | LMNAAPPPTGER1GAAKDM4E | |
| SCHEMBL10390879 | 0.77 | TDP1 (0.46) | LMNACYP1A2CYP2D6TSHRTDP1 | |
| SCHEMBL9815012 | 0.76 | CYP3A4 (0.52) | LMNACYP2D6USP2SMN1; SMN2MEN1 | |
| SCHEMBL20147117 | 0.73 | MRGPRX4 (0.53) | LMNATDP1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9169993 | 0.72 | HTR1A (0.40) | TDP1SMN1; SMN2MAPTAPPPTGER1 | |
| SCHEMBL9815002 | 0.70 | GAA (0.44) | LMNATDP1MEN1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295729-B1 | INTRAMOLECULAR NUCLEOPHILIC DISPLACEMENT COMPOUND AND USE IN PHOTOGRAPHY | AGFA-GEVAERT N.V. (BE) | 1991-09-04 | — | — | EP | disclosed |
| EP-0295729-A1 | Intramolecular nucleophilic displacement compound and use in photography | AGFA-GEVAERT N.V. (BE) | 1988-12-21 | — | — | EP | disclosed |