Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.46 |
| ▸ | PTPRC | P08575 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9815033 | 0.92 | SMN1; SMN2 (0.46) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL9815068 | 0.87 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2P2RY12LMNA | |
| SCHEMBL9815031 | 0.85 | NPSR1 (0.59) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL9815084 | 0.79 | KDM4E (0.59) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL9808436 | 0.74 | L3MBTL1 (0.84) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL3777911 | 0.72 | SMN1; SMN2 (0.68) | NPC1RAB9ASMN1; SMN2MAPTP2RY12 | |
| SCHEMBL4594453 | 0.71 | HDAC8 (0.68) | L3MBTL1MAPTKDM4EHDAC3HDAC4 | |
| SCHEMBL15899235 | 0.70 | KDM4E (0.80) | SMN1; SMN2MAPTKMT2ALMNAKDM4E | |
| SCHEMBL19501797 | 0.69 | HDAC1 (0.60) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL11957585 | 0.68 | NPSR1 (0.69) | SMN1; SMN2L3MBTL1MAPTP2RY12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447949-A1 | Optical oxygen sensor | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-25 | — | — | EP | claimed |
| EP-0447949-A1 | Optical oxygen sensor | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-25 | — | — | EP | disclosed |
| EP-0447949-A1 | Optical oxygen sensor | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-25 | — | — | EP | disclosed |