Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | IDO1 | P14902 | 1/20 | 0.59 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ESRRA | P11474 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3776520 | 0.83 | KMT2A (0.65) | KDM4ECYP1A2MTNR1AMTNR1BKMT2A | |
| SCHEMBL9815033 | 0.81 | SMN1; SMN2 (0.46) | KDM4ECYP1A2CYP2C9MTNR1AMTNR1B | |
| SCHEMBL9815031 | 0.80 | NPSR1 (0.59) | KDM4ECYP1A2KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL9815046 | 0.79 | NPC1 (0.49) | KDM4EKMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9815068 | 0.77 | NPC1 (0.59) | MTNR1AMTNR1BLMNASMN1; SMN2NPC1 | |
| SCHEMBL19027464 | 0.75 | RORC (0.54) | MTNR1AMTNR1BKMT2ALMNANPSR1 | |
| SCHEMBL3952992 | 0.75 | KMT2A (0.60) | KDM4EMTNR1AMTNR1BKMT2ALMNA | |
| SCHEMBL28124654 | 0.74 | KDM4E (0.55) | KDM4EMTNR1AMTNR1BKMT2ALMNA | |
| SCHEMBL6746166 | 0.73 | MAPT (0.62) | KDM4ECYP1A2MTNR1AMTNR1BKMT2A | |
| SCHEMBL609398 | 0.73 | KIF11 (0.58) | KDM4ECYP1A2CYP2C9IDO1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447949-A1 | Optical oxygen sensor | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-25 | — | — | EP | claimed |
| EP-0447949-A1 | Optical oxygen sensor | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-25 | — | — | EP | disclosed |