Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | EP300 | Q09472 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 2/20 | 0.53 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.51 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9815046 | 0.87 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2LMNAP2RY12 | |
| SCHEMBL3777911 | 0.87 | SMN1; SMN2 (0.68) | NPC1RAB9ASMN1; SMN2LMNAEP300 | |
| SCHEMBL9815033 | 0.84 | SMN1; SMN2 (0.46) | NPC1RAB9ASMN1; SMN2LMNAP2RY12 | |
| SCHEMBL9815031 | 0.83 | NPSR1 (0.59) | NPC1RAB9ASMN1; SMN2P2RY12 | |
| SCHEMBL19308465 | 0.78 | P2RY12 (0.73) | NPC1RAB9ASMN1; SMN2LMNAEP300 | |
| SCHEMBL9815084 | 0.77 | KDM4E (0.59) | NPC1RAB9ASMN1; SMN2LMNAMTNR1A | |
| SCHEMBL9858666 | 0.76 | ENPP2 (0.71) | NPC1RAB9ASMN1; SMN2LMNACNR1 | |
| SCHEMBL675018 | 0.76 | ENPP2 (0.71) | NPC1RAB9ASMN1; SMN2LMNACNR1 | |
| SCHEMBL9510547 | 0.76 | ENPP2 (0.71) | NPC1RAB9ASMN1; SMN2LMNACNR1 | |
| SCHEMBL10647695 | 0.76 | L3MBTL1 (0.84) | LMNACNR1CNR2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447949-A1 | Optical oxygen sensor | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-25 | — | — | EP | claimed |
| EP-0447949-A1 | Optical oxygen sensor | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-25 | — | — | EP | disclosed |