SCHEMBL9815056

SCHEMBL9815056

CC(=O)OCCC1CCC[N]C1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
CHRM5 P08912 2/20 0.32
CHRM1 P11229 2/20 0.32
CHRM3 P20309 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
PGR P06401 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
HTR1A P08908 1/20 0.32
CHRNB2 P17787 1/20 0.32
TBXA2R P21731 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA7 P36544 1/20 0.32
CHRNA4 P43681 1/20 0.32
CHRNA10 Q9GZZ6 1/20 0.32
CHRNA9 Q9UGM1 1/20 0.32
TSHR P16473 1/20 0.32
MEN1 O00255 1/20 0.32
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6050437 0.84 NAAA (0.36) SMN1; SMN2
SCHEMBL9815063 0.83 ALDH1A1 (0.38) ALDH1A1MEN1CYP3A4MAPTKMT2A
SCHEMBL8894777 0.80 EPHX1 (0.42) ALDH1A1CHRM5CHRM1CHRM3SMN1; SMN2
SCHEMBL29153766 0.80 ALDH1A1 (0.41) ALDH1A1CHRM5CHRM1CHRM3SMN1; SMN2
SCHEMBL18439 0.78 EPHX1 (0.45) ALDH1A1CHRM5CHRM1CHRM3SMN1; SMN2
SCHEMBL28720305 0.78 EPHX1 (0.45) ALDH1A1CHRM5CHRM1CHRM3SMN1; SMN2
SCHEMBL8896243 0.78 EPHX1 (0.45) ALDH1A1CHRM5CHRM1CHRM3SMN1; SMN2
SCHEMBL6050291 0.77 ALDH1A1 (0.34) ALDH1A1SMN1; SMN2MEN1CYP3A4MAPT
Hydrochloric Acid SCHEMBL28284486 0.77 EPHX1 (0.44) ALDH1A1CHRM5CHRM1CHRM3SMN1; SMN2
SCHEMBL12506840 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0447947-A1 N-(3-Phenyl-2-methylpropyl and -methyl-prop-2-enyl)-azaheterocycles BASF Aktiengesellschaft (DE) 1991-09-25 EP disclosed