Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9815083 | 0.83 | LMNA (0.40) | LMNA | |
| SCHEMBL9815056 | 0.83 | ALDH1A1 (0.33) | ALDH1A1MEN1CYP3A4MAPTKMT2A | |
| SCHEMBL697497 | 0.78 | — | — | |
| SCHEMBL2742122 | 0.78 | LMNA (0.52) | ALDH1A1MEN1CYP3A4MAPTKMT2A | |
| SCHEMBL2900647 | 0.77 | LMNA (0.55) | ALDH1A1MEN1CYP3A4MAPTKMT2A | |
| SCHEMBL9132826 | 0.77 | LMNA (0.55) | ALDH1A1MEN1CYP3A4MAPTKMT2A | |
| SCHEMBL8895551 | 0.77 | LMNA (0.55) | ALDH1A1MEN1CYP3A4MAPTKMT2A | |
| SCHEMBL2914212 | 0.75 | — | — | |
| SCHEMBL5696892 | 0.74 | ALDH1A1 (0.43) | ALDH1A1LMNANLRP3HSD17B10JAK2 | |
| SCHEMBL17029138 | 0.74 | ALDH1A1 (0.43) | ALDH1A1LMNANLRP3HSD17B10JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447947-A1 | N-(3-Phenyl-2-methylpropyl and -methyl-prop-2-enyl)-azaheterocycles | BASF Aktiengesellschaft (DE) | 1991-09-25 | — | — | EP | disclosed |