Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3781796 | 0.78 | ALDH1A1 (0.57) | KDM4ECYP1A2CYP2C9IDO1ALDH1A1 | |
| SCHEMBL8026593 | 0.76 | KDM4E (0.51) | KDM4ECYP1A2CYP2C9IDO1ALDH1A1 | |
| SCHEMBL8332038 | 0.76 | KDM4E (0.63) | KDM4ECYP1A2CYP2C9ALDH1A1MAPK1 | |
| SCHEMBL357522 | 0.74 | KDM4E (0.69) | KDM4ECYP1A2CYP2C9ALDH1A1HPGD | |
| SCHEMBL29514721 | 0.74 | KDM4E (0.69) | KDM4ECYP1A2CYP2C9ALDH1A1HPGD | |
| SCHEMBL14046286 | 0.73 | ALDH1A1 (0.61) | KDM4ECYP1A2CYP2C9IDO1ALDH1A1 | |
| SCHEMBL6774791 | 0.73 | BRD4 (0.55) | KDM4ECYP1A2CYP2C9IDO1ALDH1A1 | |
| SCHEMBL1900214 | 0.73 | RXFP1 (0.66) | KDM4EALDH1A1MAPK1HPGDMAPT | |
| SCHEMBL9815084 | 0.73 | KDM4E (0.59) | KDM4ECYP1A2CYP2C9IDO1ALDH1A1 | |
| SCHEMBL8374069 | 0.72 | KDM4E (0.46) | KDM4ECYP1A2CYP2C9IDO1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447949-A1 | Optical oxygen sensor | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-25 | — | — | EP | claimed |
| EP-0447949-A1 | Optical oxygen sensor | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-25 | — | — | EP | disclosed |