Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9815340 | 0.99 | ABCB1 (0.55) | ABCB1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9815376 | 0.78 | ADRB2 (0.53) | ADRB2 | |
| Hydrochloric Acid SCHEMBL9815343 | 0.77 | ADRB2 (0.52) | ADRB2 | |
| Alprafenone SCHEMBL1345342 | 0.70 | ADRB2 (0.54) | MEN1KMT2AADRB2 | |
| SCHEMBL29066089 | 0.70 | TUBB1 (0.67) | MEN1KMT2ALMNA | |
| SCHEMBL30504067 | 0.70 | TUBB1 (0.67) | MEN1KMT2ALMNA | |
| SCHEMBL9425925 | 0.69 | MEN1 (0.70) | MEN1KMT2AKDM4EALDH1A1POLB | |
| Alprafenone SCHEMBL1231193 | 0.69 | ADRB2 (0.53) | MEN1KMT2AADRB2 | |
| SCHEMBL9815375 | 0.69 | CASR (0.51) | ABCB1MEN1KMT2AKDM4EADRB2 | |
| SCHEMBL9815361 | 0.69 | ABCB1 (0.56) | ABCB1MEN1KMT2AKDM4EADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297435-B1 | AMINOPROPANOL DERIVATIVES OF 3-(3'-HYDROXYPHENYL)-1-PROPANONE, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | Helopharm W. Petrik GmbH & Co.KG. (DE) | 1991-10-16 | — | — | EP | claimed |