SCHEMBL98154

SCHEMBL98154

CCCCCCCCCC(CCCCCCCC(=O)OC)P(=O)(O)C(CCCCCCCCC)CCCCCCCC(=O)OC

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 5/20 0.48
PPARG P37231 1/20 0.47
PLA2G4A P47712 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
LMNA P02545 2/20 0.46
LPAR6 P43657 1/20 0.46
LPAR1 Q92633 1/20 0.46
LPAR4 Q99677 1/20 0.46
LPAR5 Q9H1C0 1/20 0.46
LPAR2 Q9HBW0 1/20 0.46
LPAR3 Q9UBY5 1/20 0.46
PLA2G2A P14555 2/20 0.45
POLB P06746 1/20 0.45
POLA1 P09884 1/20 0.45
SMPD1 P17405 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12083477 1.00 ENPP2 (0.48) ENPP2PPARGPLA2G4AL3MBTL1LMNA
SCHEMBL14681890 0.92 ENPP2 (0.54) ENPP2LPAR6LPAR1LPAR4LPAR5
SCHEMBL12190027 0.87 ENPP2 (0.41) ENPP2PPARGPLA2G4ALPAR6LPAR1
SCHEMBL27832005 0.84 ENPP2 (0.46) ENPP2PPARGPLA2G4ALPAR6LPAR1
SCHEMBL10840339 0.82 FDPS (0.61) LPAR2LPAR3SMPD1
SCHEMBL14947259 0.81 LMNA (0.53) PPARGL3MBTL1LMNAPOLBPOLA1
SCHEMBL14947261 0.81 LMNA (0.53) PPARGL3MBTL1LMNAPOLBPOLA1
SCHEMBL31556154 0.80 FDPS (0.59) LPAR2LPAR3SMPD1
SCHEMBL1330927 0.80 TSHR (0.67) LMNAPOLBPOLA1
SCHEMBL2259208 0.80 TSHR (0.67) LMNAPOLBPOLA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2660266-A2 Solid state polymerization process for polyester with phosphinic acid compounds BASF SE (DE) 2013-11-06 EP disclosed
US-8436131-B2 Solid state polymerization process for polyester with phosphinic acid compounds BASF SE (DE) 2013-05-07 US disclosed
US-20130035451-A1 Solid State Polymerization Process for Polyester with Phosphinic Acid Compounds BASF SE (DE) 2013-02-07 US disclosed
US-8258253-B2 Solid state polymerization process for polyester with phosphinic acid compounds BASF SE (DE) 2012-09-04 US disclosed
EP-2426161-A1 Solid State Polymerization Process for Polyester with Phosphinic Acid Compounds BASF SE (DE) 2012-03-07 EP disclosed
US-8030435-B2 Solid state polymerization process for polyester with phosphinic acid compounds CIBA CORPORATION (US) 2011-10-04 US disclosed
EP-2268699-B1 SOLID STATE POLYMERIZATION PROCESS FOR POLYESTER WITH PHOSPHINIC ACID COMPOUNDS BASF SE (DE) 2011-09-28 EP disclosed
EP-2268699-A1 SOLID STATE POLYMERIZATION PROCESS FOR POLYESTER WITH PHOSPHINIC ACID COMPOUNDS BASF SE (DE) 2011-01-05 EP disclosed
WO-2009121796-A1 SOLID STATE POLYMERIZATION PROCESS FOR POLYESTER WITH PHOSPHINIC ACID COMPOUNDS BASF SE (DE) 2009-10-08 WO disclosed
US-20090253888-A1 Solid state polymerization process for polyester with phosphinic acid compounds CIBA CORPORATION 2009-10-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130035451-A1 Solid State Polymerization Process for Polyester with Phosphinic Acid Compounds PHOSPHO1, PIK3C2A, PIK3C2B ENPP2 505/4885PPARG 4472/4885PLA2G4A 70/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.