Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12919849 | 0.86 | TSHR (0.58) | TSHRTDP1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL1582827 | 0.81 | TSHR (0.58) | TSHRTDP1ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL9477771 | 0.81 | BACE1 (0.44) | TSHRALDH1A1CYP3A4ALOX15MAPK1 | |
| SCHEMBL1890141 | 0.79 | S100A4 (0.40) | TSHRALDH1A1CYP3A4ALOX15PDK1 | |
| SCHEMBL12572189 | 0.79 | S100A4 (0.40) | TSHRALDH1A1CYP3A4ALOX15PDK1 | |
| SCHEMBL10477064 | 0.79 | ATM (0.55) | TSHRTDP1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL2148284 | 0.79 | LOXL2 (0.43) | TSHRTDP1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL5667314 | 0.79 | TDP1 (0.58) | TSHRTDP1ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL2499076 | 0.77 | MAPT (0.58) | TSHRTDP1ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL13498001 | 0.77 | KAT2B (0.42) | TSHRTDP1ALDH1A1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297607-B1 | GAMMA-L-GLUTAMYL-4-NITROANILIDE DERIVATIVES AND PROCESS FOR DETERMINING GAMMA-GTP ACTIVITY USING THE SAME | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4851572-A | DIAGNOSIS OF LIVER AND BILE DUCT DISORDERS, ALCOHOLISM | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| EP-0297607-A1 | Gamma-L-glutamyl-4-nitroanilide derivatives and process for determining gamma-GTP activity using the same | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1989-01-04 | — | — | EP | disclosed |