Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19662718 | 0.88 | LOXL2 (0.43) | LOXL2MAPTALDH1A1LMNAAPP | |
| SCHEMBL13498001 | 0.86 | KAT2B (0.42) | MAPTALDH1A1LMNAAPPALOX15 | |
| SCHEMBL13888388 | 0.84 | APP (0.38) | MAPTALDH1A1LMNAAPPALOX15 | |
| SCHEMBL3898485 | 0.84 | POLB (0.38) | MAPTALDH1A1LMNAAPPALOX15 | |
| SCHEMBL13179034 | 0.82 | GSR (0.41) | MAPTALDH1A1APPVCAM1 | |
| SCHEMBL16281668 | 0.82 | APP (0.41) | MAPTALDH1A1LMNAAPPALOX15 | |
| SCHEMBL16362119 | 0.80 | ALDH1A1 (0.40) | LOXL2MAPTALDH1A1LMNAPDK1 | |
| SCHEMBL17053079 | 0.80 | ALDH1A1 (0.39) | LOXL2MAPTALDH1A1LMNATSHR | |
| SCHEMBL9815413 | 0.79 | TSHR (0.55) | MAPTALDH1A1LMNAALOX15TSHR | |
| SCHEMBL14282660 | 0.79 | LOXL2 (0.38) | LOXL2MAPTALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250179572-A1 | Photoactive Compounds and Methods for Biomolecule Detection and Sequencing | VIBRANT HOLDINGS, LLC | 2025-06-05 | — | — | US | disclosed |
| US-12152279-B2 | Photoactive compounds and methods for biomolecule detection and sequencing | VIBRANT HOLDINGS, LLC (US) | 2024-11-26 | — | — | US | disclosed |
| WO-2023180237-A1 | METHOD AND COMPOUND | ATDBio Limited (GB) | 2023-09-28 | — | — | WO | disclosed |
| EP-4249495-A1 | METHOD FOR THE PURIFICATION OF POLYNUCLEOTIDES AND ANALOGUES THEREOF | ATDBio Limited (GB) | 2023-09-27 | — | — | EP | disclosed |
| WO-2023099471-A1 | METHOD FOR PRODUCING POLYNUCLEOTIDES | ATDBio Limited (GB) | 2023-06-08 | — | — | WO | disclosed |
| EP-4186914-A1 | METHOD FOR PRODUCING POLYNUCLEOTIDES | ATDBio Limited (GB) | 2023-05-31 | — | — | EP | disclosed |
| US-20220162698-A1 | PHOTOACTIVE COMPOUNDS AND METHODS FOR BIOMOLECULE DETECTION AND SEQUENCING | VIBRANT HOLDINGS, LLC | 2022-05-26 | — | — | US | disclosed |
| US-11168365-B2 | Photoactive compounds and methods for biomolecule detection and sequencing | VIBRANT HOLDINGS, LLC (US) | 2021-11-09 | — | — | US | disclosed |
| US-10907194-B2 | Synthesis of four-color 3′-O-allyl modified photocleavable fluorescent nucleotides and related methods | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2021-02-02 | — | — | US | disclosed |
| US-20200095635-A1 | Photoactive Compounds and Methods for Biomolecule Detection and Sequencing | VIBRANT HOLDINGS, LLC | 2020-03-26 | — | — | US | disclosed |
| US-7713698-B2 | Determining sequence of preferential DNA sequences | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2010-05-11 | — | — | US | disclosed |
| US-20100041029-A1 | SYNTHESIS OF FOUR COLOR 3'O-ALLYL, MODIFIED PHOTOCLEAVABLE FLUORESCENT NUCLEOTIDES AND RELATED METHODS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2010-02-18 | — | — | US | disclosed |
| US-7635578-B2 | Sequencing; solid phase synthesis; primer hybridization | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2009-12-22 | — | — | US | disclosed |
| US-7622279-B2 | Photocleavable fluorescent nucleotides for DNA sequencing on chip constructed by site-specific coupling chemistry | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2009-11-24 | — | — | US | disclosed |
| US-20080227742-A1 | Photocleavable oligonucleotide and uses thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-09-18 | — | — | US | disclosed |
| US-20080199868-A1 | Sequencing; solid phase synthesis; primer hybridization | NATIONAL SCIENCE FOUNDATION | 2008-08-21 | — | — | US | disclosed |
| US-20080131895-A1 | Determining sequence of preferential DNA sequences | NATIONAL SCIENCE FOUNDATION | 2008-06-05 | — | — | US | disclosed |
| US-7345159-B2 | Massive parallel method for decoding DNA and RNA | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2008-03-18 | — | — | US | disclosed |
| US-20070275387-A1 | Photocleavable Fluorescent Nucleotides for Dna Sequencing on Chip Constructed by Site-Specific Coupling Chemistry | TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE (US) | 2007-11-29 | — | — | US | disclosed |
| WO-2007053702-A2 | SYNTHESIS OF FOUR COLOR 3'-O-ALLYL MODIFIED PHOTOCLEAVABLE FLUORESCENT NUCLEOTIDES AND RELATED METHODS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2007-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275387-A1 | Photocleavable Fluorescent Nucleotides for Dna Sequencing on Chip Constructed by Site-Specific Coupling Chemistry | RNGTT, STUB1, POLM | LOXL2 3262/4885MAPT 3402/4885ALDH1A1 1422/4885 |
| US-20080199868-A1 | Sequencing; solid phase synthesis; primer hybridization | RNGTT, POLL, POLN | LOXL2 4627/4885MAPT 2951/4885ALDH1A1 1479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.