Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.53 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | STAT1 | P42224 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28742452 | 0.87 | ALDH1A1 (0.61) | RAB9AALDH1A1CYP1A2NPSR1SIRT2 | |
| SCHEMBL791661 | 0.85 | ALDH1A1 (0.59) | RAB9AALDH1A1CYP1A2NPSR1SIRT2 | |
| SCHEMBL9815410 | 0.84 | RAB9A (0.53) | RAB9AALDH1A1CYP1A2NPSR1HSD17B10 | |
| SCHEMBL25140423 | 0.84 | ALDH1A1 (0.56) | RAB9AALDH1A1SIRT2SIRT3POLB | |
| SCHEMBL24728477 | 0.84 | ALDH1A1 (0.56) | RAB9AALDH1A1SIRT2SIRT3HSD17B10 | |
| SCHEMBL28977953 | 0.83 | RAB9A (0.55) | RAB9AALDH1A1CYP1A2NPSR1SIRT2 | |
| SCHEMBL30167080 | 0.83 | RAB9A (0.55) | RAB9AALDH1A1CYP1A2NPSR1SIRT2 | |
| SCHEMBL6709375 | 0.82 | ALDH1A1 (0.73) | RAB9AALDH1A1KMT2AMAOBKDM4E | |
| SCHEMBL6692993 | 0.81 | MAPT (0.49) | RAB9AALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL13542850 | 0.80 | TOP2A (0.57) | RAB9AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297607-B1 | GAMMA-L-GLUTAMYL-4-NITROANILIDE DERIVATIVES AND PROCESS FOR DETERMINING GAMMA-GTP ACTIVITY USING THE SAME | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4851572-A | DIAGNOSIS OF LIVER AND BILE DUCT DISORDERS, ALCOHOLISM | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| EP-0297607-A1 | Gamma-L-glutamyl-4-nitroanilide derivatives and process for determining gamma-GTP activity using the same | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1989-01-04 | — | — | EP | disclosed |