Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | IDH1 | O75874 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9815416 | 0.84 | RAB9A (0.63) | ALDH1A1RAB9AKDM4EGAASTAT1 | |
| SCHEMBL25140423 | 0.84 | ALDH1A1 (0.56) | ALDH1A1RAB9ACYP3A4IDH1MGLL | |
| SCHEMBL6709375 | 0.82 | ALDH1A1 (0.73) | ALDH1A1RAB9ACYP3A4IDH1KDM4E | |
| SCHEMBL13542850 | 0.80 | TOP2A (0.57) | ALDH1A1RAB9ACYP3A4TOP2ATOP2B | |
| SCHEMBL7671540 | 0.80 | ALDH1A1 (0.63) | ALDH1A1RAB9ACYP3A4IDH1KDM4E | |
| SCHEMBL18019337 | 0.80 | ALDH1A1 (0.58) | ALDH1A1RAB9ACYP3A4IDH1KDM4E | |
| SCHEMBL27312515 | 0.78 | ALDH1A1 (0.61) | ALDH1A1RAB9ACYP3A4IDH1KDM4E | |
| SCHEMBL24936558 | 0.78 | ALDH1A1 (0.49) | ALDH1A1RAB9ACYP3A4IDH1MGLL | |
| SCHEMBL27413665 | 0.78 | ALDH1A1 (0.49) | ALDH1A1RAB9ACYP3A4IDH1MGLL | |
| SCHEMBL2385123 | 0.78 | ALDH1A1 (0.66) | ALDH1A1CYP3A4IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253284-A1 | DRUG CONJUGATE AND USE THEREOF | 百奥泰生物制药股份有限公司 | 2022-12-08 | — | — | WO | disclosed |