Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BID | P55957 | 6/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.57 |
| ▸ | BCL2L1 | Q07817 | 5/20 | 0.57 |
| ▸ | BAK1 | Q16611 | 5/20 | 0.57 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.57 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | PPARA | Q07869 | 1/20 | 0.57 |
| ▸ | EP300 | Q09472 | 1/20 | 0.57 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.57 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.57 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | F7 | P08709 | 2/20 | 0.49 |
| ▸ | F3 | P13726 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL4267974 | 0.94 | BID (0.58) | BIDMCL1BCL2L1BAK1KAT8 | |
| Acetone SCHEMBL25277794 | 0.94 | BID (0.54) | BIDMCL1BCL2L1BAK1KAT8 | |
| Acetic Acid SCHEMBL27988491 | 0.93 | BID (0.67) | BIDMCL1BCL2L1BAK1KAT8 | |
| Acetic Acid SCHEMBL7637677 | 0.93 | BID (0.67) | BIDMCL1BCL2L1BAK1KAT8 | |
| Benzene SCHEMBL9052791 | 0.92 | HTR1A (0.58) | BIDMCL1BCL2L1BAK1KAT8 | |
| Propionic Acid SCHEMBL8222391 | 0.91 | BID (0.55) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL20232 | 0.90 | HTR1A (0.60) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL29450060 | 0.90 | HTR1A (0.60) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL9319489 | 0.90 | HTR1A (0.60) | BIDMCL1BCL2L1BAK1KAT8 | |
| Urea SCHEMBL27306115 | 0.89 | BID (0.53) | BIDMCL1BCL2L1BAK1KAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257845-B1 | METHOD OF PRODUCING VARIEGATED PLANTS | Taguchi, Masayasu (JP) | 1991-10-16 | — | — | EP | claimed |
| EP-0257845-A2 | Method of producing variegated plants | Taguchi, Masayasu (JP) | 1988-03-02 | — | — | EP | claimed |
| CN-110719768-A | Powder comprising crystals having inclusions encapsulated therein | 西姆莱斯有限公司 | 2020-01-21 | — | — | CN | disclosed |
| CN-105017240-A | Pesticidal compositions | DOW AGROSCIENCES LLC | 2015-11-04 | — | — | CN | disclosed |
| CN-101033400-A | Stable green fluorescence powder and plasma displaying panel using the same | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 2007-09-12 | — | — | CN | disclosed |
| CN-1965054-A | Green light emitting phosphor material and plasma display panel using the same | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 2007-05-16 | — | — | CN | disclosed |
| EP-0257845-B1 | METHOD OF PRODUCING VARIEGATED PLANTS | Taguchi, Masayasu (JP) | 1991-10-16 | — | — | EP | disclosed |
| EP-0257845-A2 | Method of producing variegated plants | Taguchi, Masayasu (JP) | 1988-03-02 | — | — | EP | disclosed |