SCHEMBL9815628

SCHEMBL9815628

CCCCc1ccc(C=C(C)C(=O)OC)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.47
PLK1 P53350 1/20 0.46
ALDH1A1 P00352 4/20 0.46
HPGD P15428 3/20 0.46
HSD17B10 Q99714 1/20 0.46
THRB P10828 2/20 0.45
THRA P10827 1/20 0.45
GRIN2D O15399 1/20 0.44
GRIN3B O60391 1/20 0.44
GRIN1 Q05586 1/20 0.44
GRIN2A Q12879 1/20 0.44
GRIN2B Q13224 1/20 0.44
GRIN2C Q14957 1/20 0.44
GRIN3A Q8TCU5 1/20 0.44
RARB P10826 1/20 0.43
ABCG2 Q9UNQ0 1/20 0.42
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
TRPV1 Q8NER1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL986697 0.83 AKR1C3 (0.55) POLBPLK1ALDH1A1HPGDHSD17B10
SCHEMBL29638051 0.81 ABCG2 (0.39) ALDH1A1ABCG2NPC1RAB9ASMN1; SMN2
SCHEMBL23582399 0.77 CA2 (0.44)
SCHEMBL21065592 0.77 MAPT (0.53) PLK1ALDH1A1HPGDTHRBNPC1
SCHEMBL10692594 0.77 CA2 (0.50) POLBPLK1ALDH1A1HPGDHSD17B10
SCHEMBL16065669 0.75 MAPT (0.46) POLBALDH1A1THRBNPC1RAB9A
SCHEMBL9335450 0.75 KDM4E (0.55) POLBALDH1A1ABCG2
SCHEMBL12276489 0.75 TRPA1 (0.55) NPC1RAB9A
SCHEMBL10277230 0.75 TRPA1 (0.55) NPC1RAB9A
SCHEMBL10277228 0.75 TRPA1 (0.55) NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0257845-B1 METHOD OF PRODUCING VARIEGATED PLANTS Taguchi, Masayasu (JP) 1991-10-16 EP disclosed
EP-0257845-A2 Method of producing variegated plants Taguchi, Masayasu (JP) 1988-03-02 EP disclosed